Prof. Dr. Silvia Capellino
Leitung Forschungsgruppe Neuroimmunologie
- 2020Verleihung des Titels "Außerplanmäßige Professorin" durch die Universität Duisburg-Essen
- Seit 2017Fakultätsratsmitglied an der medizinischen Fakultät der Universität Duisburg-Essen
- Seit 2016Leiterin der Nachwuchsgruppe "Neuroimmunologie" am Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo)
- 2016-2019Marie Skłodowska-Curie Stipendiatin am Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo)
- 2015-2016PostDoc (Justus-Liebig-Universität Gießen und Kerckhoff Klinik GmbH, Bad Nauheim)
- 2014Elternzeit
- 2012-2013Senior Scientist (The Johns Hopkins University, USA)
- 2012Habilitation (Universität Regensburg)
- 2007-2012PostDoc (Universitätsklinikum Regensburg)
- 2007Promotion (Universität Genua, Italien und Universitätsklinikum Regensburg)
- 2003Diplom in Biologie (Universität Genua, Italien)
Hier finden Sie die Schlüsselpublikationen ab 2010, die am IfADo entstanden sind.
Fleige L, Fillatreau S, Claus M, Capellino S:
Additional use of α-IgM antibodies potentiates CpG ODN2006-induced B cell activation by targeting mainly naïve and marginal zone-like B cells. Cell Immunol 403-404: 104846 (2024) (12 pp)
Claus M, Capellino S:
Catecholamines and immunomodulation. In: Konsman JP, Reyes TM (eds): Neuroendocrine-immune system interactions (pp 105-133). Cham: Springer, 2023 (Masterclass in Neuroendocrinology, Vol. 13)
Larra M, Capellino S, Schwendich E, von Haugwitz L, Reinders J, Wascher E:
Immediate and delayed salivary cytokine responses during repeated exposures to Cold Pressor stress. Neuroimmunomodulation 30: 81–92 (2023)
Schwendich E, Salinas Tejedor L, Schmitz G, Rickert M, Steinmeyer J, Rehart S, Tsiami S, Braun J, Baraliakos X, Reinders J, Neumann E, Müller-Ladner U, Capellino S:
Modulation of dopamine receptors on osteoblasts as a possible therapeutic strategy for inducing bone formation in arthritis. Cells 11 (10): 1609 (2022) (20 pp)
Gajewski PD, Getzmann S, Bröde P, Burke M, Cadenas C, Capellino S, Claus M, Genç E, Golka K, Hengstler JG, Kleinsorge T, Marchan R, Nitsche MA, Reinders J, van Thriel C, Watzl C, Wascher E:
Impact of biological and lifestyle factors on cognitive aging and work ability in the Dortmund Vital Study: Protocol of an interdisciplinary, cross-sectional, and longitudinal study. JMIR Res Protoc 11 (3): e32352 (2022) (18 pp)
Wieber K, Fleige L, Tsiami S, Reinders J, Braun J, Baraliakos X, Capellino S:
Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis. Sci Re17 (1): 5985 (2022) (15 pp)
Capellino S, Engler H, Rohleder N (eds):
14th Conference of the German Endocrine-Brain-Immune-Network (GEBIN), Erlangen, March 30 – April 1, 2022. Abstracts. Basel: Karger, 2022 (Neuroimmunomodulation, Vol. 29, Suppl. 1)
Peifer C, Hagemann V, Claus M, Larra MF, Aust F, Kühn M, Owczarek M, Broede P, Pacharra M, Steffens H, Watzl C, Wascher E, Capellino S:
Low self-reported stress despite immune-physiological changes in paramedics during rescue operations. EXCLI J 20: 792-811 (2021)
Van Nie L, Salinas-Tejedor L, Dychus N, Fasbender F, Hülser M-L, Cutolo M, Rehart S, Neumann E, Müller-Ladner U, Capellino S:
Dopamine induces in vitro migration of synovial fibroblast from patients with rheumatoid arthritis. Sci Rep 10: 11928 (2020) (13 pp)
Capellino S, Claus M, Watzl C:
Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine. Cell Mol Immunol 17: 705-711 (2020)
Novaira HJ, Negron AL, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Levine JE, Wolfe A, Wondisford FE, Radovick S:
Impairments in the reproductive axis of female mice lacking estrogen receptor β in GnRH neurons. Am J Physiol Endocrinol Metab 315: E1019–E1033 (2018)
Böhm M, Apel M, Lowin T, Lorenz J, Jenei-Lanzl Z, Capellino S, Dosoki H, Luger TA, Straub RH, Grässel S:
α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients. Biochem Pharmacol 116: 89-99 (2016)
Novaira HJ, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Wolfe A, Wondisford F, Radovick S:
Development and Characterization of Novel Rat Anti-mERβ Sera. Endocrinology 157: 2844-2852 (2016)
Jenei-Lanzl Z, Capellino S, Kees F, Fleck M, Lowin T, Straub RH:
Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis. Ann Rheum Dis 74: 444-451 (2015)
van der Goes MC, Straub RH, Wenting MJ, Capellino S, Jacobs JW, Jahangier ZN, Rauch L, Bijlsma JW, Lafeber FP:
Intra-articular glucocorticoid injections decrease the number of steroid hormone receptor positive cells in synovial tissue of patients with persistent knee arthritis. Ann Rheum Dis 71: 1552-1558 (2015)
Capellino S, Cosentino M, Luini A, Bombelli R, Lowin T, Cutolo M, Marino F, Straub RH:
Increased expression of dopamine receptors in synovial fibroblasts from patients with rheumatoid arthritis: inhibitory effects of dopamine on interleukin-8 and interleukin-6. Arthritis Rheumatol 66: 2685-2693 (2014)
Capellino S, Straub RH, Cutolo M:
Aromatase and regulation of the estrogen-to-androgen ratio in synovial tissue inflammation: common pathway in both sexes. Ann N Y Acad Sci 1317: 24-31 (2014)
Lowin T, Weidler C, Jenei-Lanzl Z, Capellino S, Baerwald CG, Buttgereit F, Straub RH:
Relationship between placenta growth factor 1 and vascularization, dehydroepiandrosterone sulfate to dehydroepiandrosterone conversion, or aromatase expression in patients with rheumatoid arthritis and patients with osteoarthritis. Arthritis Rheum 64: 1799-1808 (2012)
Capellino S, Weber K, Gelder M, Härle P, Straub RH:
First appearance and location of catecholaminergic cells during experimental arthritis and elimination by chemical sympathectomy. Arthritis Rheum 64: 1110-1118 (2012)
Graf N, McLean M, Capellino S, Schölmerich J, Murray GI, El-Omar EM, Straub RH:
Loss of sensory and noradrenergic innervation in benign colorectal adenomatous polyps--a putative role of semaphorins 3F and 3A. Neurogastroenterol Motil 24: 120-128, e83 (2012)
Probst C, Pongratz G, Capellino S, Szeimies RM, Schölmerich J, Fleck M, Salzberger B, Ehrenstein B:
Cryptococcosis mimicking cutaneous cellulitis in a patient suffering from rheumatoid arthritis: a case report. BMC Infect Dis 10: 239 (2010)
Capellino S, Cosentino M, Wolff C, Schmidt M, Grifka J, Straub RH:
Catecholamine-producing cells in the synovial tissue during arthritis: modulation of sympathetic neurotransmitters as new therapeutic target. Ann Rheum Dis 69: 1853-1860 (2010)
Haas S, Capellino S, Phan NQ, Böhm M, Luger TA, Straub RH, Ständer S:
Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis. J Dermatol Sci. 58: 193-197 (2010)
Cutolo M, Brizzolara R, Atzeni F, Capellino S, Straub RH, Puttini PC:
The immunomodulatory effects of estrogens: clinical relevance in immune-mediated rheumatic diseases. Ann N Y Acad Sci 1193: 36-42 (2010)
Ferrero S, Haas S, Remorgida V, Camerini G, Fulcheri E, Ragni N, Straub RH, Capellino S:
Loss of sympathetic nerve fibers in intestinal endometriosis. Fertil Steril 94: 2817-2819 (2010)
Schmidt M, Hartung R, Capellino S, Cutolo M, Pfeifer-Leeg A, Straub RH:
Estrone/17beta-estradiol conversion to, and tumor necrosis factor inhibition by, estrogen metabolites in synovial cells of patients with rheumatoid arthritis and patients with osteoarthritis. Arthritis Rheum 60: 2913-2922 (2009)
Capellino S, Montagna P, Villaggio B, Soldano S, Straub RH, Cutolo M:
Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia. Clin Exp Rheumatol 26: 903-909 (2008)
Cutolo M, Capellino S, Straub RH:
Oestrogens in rheumatic diseases: friend or foe? Rheumatology (Oxford) 47 (Suppl 3): iii2-5 (2008)
Hier finden Sie die Publikationen ab 2010, die am IfADo entstanden sind.
Fleige L, Fillatreau S, Claus M, Capellino S:
Additional use of α-IgM antibodies potentiates CpG ODN2006-induced B cell activation by targeting mainly naïve and marginal zone-like B cells. Cell Immunol 403-404: 104846 (2024) (12 pp)
Claus M, Capellino S:
Catecholamines and immunomodulation. In: Konsman JP, Reyes TM (eds): Neuroendocrine-immune system interactions (pp 105-133). Cham: Springer, 2023 (Masterclass in Neuroendocrinology, Vol. 13)
Larra M, Capellino S, Schwendich E, von Haugwitz L, Reinders J, Wascher E:
Immediate and delayed salivary cytokine responses during repeated exposures to Cold Pressor stress. Neuroimmunomodulation 30: 81–92 (2023)
Schwendich E, Salinas Tejedor L, Schmitz G, Rickert M, Steinmeyer J, Rehart S, Tsiami S, Braun J, Baraliakos X, Reinders J, Neumann E, Müller-Ladner U, Capellino S:
Modulation of dopamine receptors on osteoblasts as a possible therapeutic strategy for inducing bone formation in arthritis. Cells 11 (10): 1609 (2022) (20 pp)
Gajewski PD, Getzmann S, Bröde P, Burke M, Cadenas C, Capellino S, Claus M, Genç E, Golka K, Hengstler JG, Kleinsorge T, Marchan R, Nitsche MA, Reinders J, van Thriel C, Watzl C, Wascher E:
Impact of biological and lifestyle factors on cognitive aging and work ability in the Dortmund Vital Study: Protocol of an interdisciplinary, cross-sectional, and longitudinal study. JMIR Res Protoc 11 (3): e32352 (2022) (18 pp)
Wieber K, Fleige L, Tsiami S, Reinders J, Braun J, Baraliakos X, Capellino S:
Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis. Sci Re17 (1): 5985 (2022) (15 pp)
Capellino S, Engler H, Rohleder N (eds):
14th Conference of the German Endocrine-Brain-Immune-Network (GEBIN), Erlangen, March 30 – April 1, 2022. Abstracts. Basel: Karger, 2022 (Neuroimmunomodulation, Vol. 29, Suppl. 1)
Peifer C, Hagemann V, Claus M, Larra MF, Aust F, Kühn M, Owczarek M, Broede P, Pacharra M, Steffens H, Watzl C, Wascher E, Capellino S:
Low self-reported stress despite immune-physiological changes in paramedics during rescue operations. EXCLI J 20: 792-811 (2021)
Van Nie L, Salinas-Tejedor L, Dychus N, Fasbender F, Hülser M-L, Cutolo M, Rehart S, Neumann E, Müller-Ladner U, Capellino S:
Dopamine induces in vitro migration of synovial fibroblast from patients with rheumatoid arthritis. Sci Rep 10: 11928 (2020) (13 pp)
Capellino S, Claus M, Watzl C:
Regulation of natural killer cell activity by glucocorticoids, serotonin, dopamine, and epinephrine. Cell Mol Immunol 17: 705-711 (2020)
Novaira HJ, Negron AL, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Levine JE, Wolfe A, Wondisford FE, Radovick S:
Impairments in the reproductive axis of female mice lacking estrogen receptor β in GnRH neurons. Am J Physiol Endocrinol Metab 315: E1019–E1033 (2018)
Böhm M, Apel M, Lowin T, Lorenz J, Jenei-Lanzl Z, Capellino S, Dosoki H, Luger TA, Straub RH, Grässel S:
α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients. Biochem Pharmacol 116: 89-99 (2016)
Novaira HJ, Graceli JB, Capellino S, Schoeffield A, Hoffman GE, Wolfe A, Wondisford F, Radovick S:
Development and Characterization of Novel Rat Anti-mERβ Sera. Endocrinology 157: 2844-2852 (2016)