Dr. Reham Hassan Reyad Khalil Alkashef

Scientific staff

Head of department
Prof. Dr. Jan G. Hengstler
Secretariat
Monika Turajski
Address
Ardeystr. 67
44139 Dortmund

Here you will find the Publications from 2010 onwards that were produced at IfADo.

Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis. J Hepatol 80: 268-281 (2024)
A liver digital twin for in silico testing of cellular and inter-cellular mechanisms in regeneration after drug-induced damage. iScience 27 (2): 108077 (2024) (26 pp)
Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats. Arch Toxicol 98: 1081-1093 (2024)
Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats. Arch Toxicol 98: 1533-1542 (2024)
Role of albumin in the metabolism and excretion of ochratoxin A. Mycotoxin Res. 2024 May 14. Epub ahead of print.
Cognitive functions, neurotransmitter alterations, and hippocampal microstructural changes in mice caused by feeding on western diet. Cells 12 (18): 2331 (2023) (20 pp)
Increased sinusoidal export of drug glucuronides is a compensative mechanism in liver cirrhosis of mice. Front Pharmacol 14: 1279357 (2023) (14 pp)
In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin. Front Bioeng Biotechnol 11: 1049564 (2023) (21 pp)
Vinpocetine protects against chloroquine-induced cardiotoxicity by mitigating oxidative stress. Arch Toxicol 97: 2763–2770 (2023)
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity. Arch Toxicol 96: 2967–2981 (2022)
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Arch Toxicol 96: 3349–3361 (2022)
Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury. Elife 11: e78540 (2022) (28 pp)
Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins. Arch Toxicol 96: 3067-3076 (2022)
Transcriptomic cross-species analysis of chronic liver disease reveals consistent regulation between humans and mice. Hepatol Commun 6: 161-177 (2022)
Comparative histological analysis of the skin for forensic investigation of some animal species. EXCLI J 21: 1286-1298 (2022)