Dr. Nachiket Vartak

Group Leader Bioimaging

Bioimaging

+49 231 1084-464

nash@ifado.de

Publications in Pubmed

Head of department

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

since 2022
Head of Bioimaging Group, Dept. of Toxicology, Leibniz-Research Centre for Working Environment and Human Factors (IfADo), Dortmund
2016-2022
Junior Group Leader, Department of Toxicology Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund
2014-2016
Postdoc, Department of Toxicology Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund
2011-2014
Postdoc, Max-Planck-Institute (MPI-MOPH), Dortmund
2007-2011
Doctoral Reseach, Max-Planck-Institute (MPI-MOPH), Dortmund
2004-2006
Academic studies (MSc. Biotechnology), Indian Institute of Technology (IITB), Mumbai, India
2001-2004
Academic studies (BSc. Life Sciences and Biochemistry), St. Xavier's College, University of Mumbai, India

Here you will find the Publications from 2010 onwards that were produced at IfADo. For all other publications of our scientific staff, please look at the links to other databases such as Pubmed.

Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG:

Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis. J Hepatol 80: 268-281 (2024)

Bloch D, Diel P, Epe B, Hellwig M, Lampen A, Mally A, Marko D, Villar Fernández MA, Guth S, Roth A, Marchan R, Ghallab A, Cadenas C, Nell P, Vartak N, van Thriel C, Luch A, Schmeisser S, Herzler M, Landsiedel R, Leist M, Marx-Stoelting P, Tralau T, Hengstler JG:

Basic concepts of mixture toxicity and relevance for risk evaluation and regulation. Arch Toxicol 97: 3005-3017 (2023)

Vartak N, Hengstler JG:

Reply to 21-1766: Challenging the dogma of canalicular bile flow. (Correspondence). Hepatology 75: 493-494 (2022)

Vartak N, Elferink RO, van de Graaf S, Drasdo D, Hengstler J:

Reply (to: Javitt NB: Intravital Dynamic and Correlative Imaging Reveals Diffusion-Dominated Canalicular and Flow-Augmented Ductular Bile Flux (Letter to the editor). https://doi.org/10.1002/hep.31746). Hepatology 76 (3): E58 (2022)

Brecklinghaus T, Albrecht W, Kappenberg F, Duda J, Vartak N, Edlund K, Marchan R, Ghallab A, Cadenas C, Günther G, Leist M, Zhang M, Gardner I, Reinders J, Russel FGM, Foster AJ, Williams DP, Damle-Vartak A, Grandits M, Ecker G, Kittana N, Rahnenführer J, Hengstler JG:

The hepatocyte export carrier inhibition assay improves the separation of hepatotoxic from non-hepatotoxic compounds. Chem Biol Interact 351: 109728 (2022) (16 pp)

Schnabl B, Arteel GE, Stickel F, Hengstler JG, Vartak N, Ghallab A, Dooley S, Li Y, Schwabe RF:

Liver specific, systemic and genetic contributors to alcohol-related liver disease progression. Z Gastroenterol 60: 36-44 (2022)

Nell P, Kattler K, Feuerborn D, Hellwig B, Rieck A, Salhab A, Lepikhov K, Gasparoni G, Thomitzek A, Belgasmi K, Blüthgen N, Morkel M, Küppers-Munther B, Godoy P, Hay DC, Cadenas C, Marchan R, Vartak N, Edlund K, Rahnenführer J, Walter J, Hengstler JG:

Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells. J Hepatol 77: 1386-1398 (2022)

Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG:

In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay. Toxicol Lett 368: 33-46 (2022)

Vartak N, Hengstler J:

Reply (To the editor). (Correspondence). Hepatology 74: 1133 (2021)

Vartak N, Guenther G, Joly F, Damle‐Vartak A, Wibbelt G, Fickel J, Jörs S, Begher‐Tibbe B, Friebel A, Wansing K, Ghallab A, Rosselin R, Boissier N, Vignon‐Clementel I, Hedberg C, Geisler F, Hofer H, Hoehme S, Drasdo D, Hengstler JG:

Intravital dynamic and correlative imaging of mouse livers reveals diffusion-dominated canalicular and flow-augmented ductular bile flux. Hepatology 73: 1531-1550 (2021)