Dr. Maiju Myllys

Scientific staff

Intravital Toxicology

+49 231 1084-216

myllys@ifado.de

Leader

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

Publications

Here you will find the Publications from 2010 onwards that were produced at IfADo.

Custodio RJP, Hobloss Z, Myllys M, Hassan R, González D, Reinders J, Bornhorst J, Weishaupt AK, Seddek AL, Abbas T, Friebel A, Hoehme S, Getzmann S, Hengstler JG, van Thriel C, Ghallab A:

Cognitive functions, neurotransmitter alterations, and hippocampal microstructural changes in mice caused by feeding on western diet. Cells 12 (18): 2331 (2023) (20 pp)

Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek A-l, Marchan R, Cramer B, Humpf H-U, Hoehme S, Degen GH, Hengstler JG, Ghallab A:

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Arch Toxicol 96: 3349–3361 (2022)

Hassan R, Myllys M, Brackhagen L, Hobloss Z, González D, Seddek A-L, Friebel A, Hoehme S, Marchan R, Trauner M, Hengstler JG, Ghallab A:

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins. Arch Toxicol 96: 3067-3076 (2022)

Holland CH, Ramirez Flores RO, Myllys M, Hassan R, Edlund K, Hofmann U, Marchan R, Cadenas C, Reinders J, Hoehme S, Seddek AL, Dooley S, Keitel V, Godoy P, Begher-Tibbe B, Trautwein C, Rupp C, Mueller S, Longerich T, Hengstler JG, Saez-Rodriguez J, Ghallab A:

Transcriptomic cross-species analysis of chronic liver disease reveals consistent regulation between humans and mice. Hepatol Commun 6: 161-177 (2022)

Remetic J, Ghallab A, Hobloss Z, Brackhagen L, Hassan R, Myllys M, Radun R, Mlitz V, Zhu C, Baumgartner M, Schrottmaier WC, Mussbacher M, Timelthaler G, Scharnagl H, Stojakovic T, Assinger A, Fuchs CD, Hengstler JG, Trauner M:

Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance. Hepatology 75: 1095-1109 (2022)

Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG:

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity. J Hepatol 77: 71-83 (2022)

Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek A-L, Marchan R, Cadenas C, Cramer B, Humpf H-U, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A:

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity. Arch Toxicol 96: 2967–2981 (2022)

Myllys M:

Prediction of neoadjuvant chemotherapy response in breast cancer. (Letter to the editor). EXCLI J 20: 625-627 (2021)

Schneider KM, Elfers C, Ghallab A, Schneider CV, Galvez EJC, Mohs A, Gui W, Candels LS, Wirtz TH, Zuehlke S, Spiteller M, Myllys M, Roulet A, Ouzerdine A, Lelouvier B, Kilic K, Liao L, Nier A, Latz E, Bergheim I, Thaiss CA, Hengstler JG, Strowig T, Trautwein C:

Intestinal dysbiosis amplifies acetaminophen-induced acute liver injury. Cell Mol Gastroenterol Hepatol 11: 909-933 (2021)

Ghallab A, Hassan R, Myllys M, Albrecht W, Friebel A, Hoehme S, Hofmann U, Seddek AL, Braeuning A, Kuepfer L, Cramer B, Humpf HU, Boor P, Degen GH, Hengstler JG:

Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney. Arch Toxicol 95: 2163-2177 (2021)

Ghallab A, Myllys M, Friebel A, Duda J, Edlund K, Halilbasic E, Vucur M, Hobloss Z, Brackhagen L, Begher-Tibbe B, Hassan R, Burke M, Genc E, Frohwein LJ, Hofmann U, Holland CH, González D, Keller M, Seddek A-l, Abbas T, Mohammed ESI, Teufel A, Itzel T, Metzler S, Marchan R, Cadenas C, Watzl C, Nitsche MA, Kappenberg F, Luedde T, Longerich T, Rahnenführer J, Hoehme S, Trauner M, Hengstler JG:

Spatio-temporal multiscale analysis of western diet-fed mice reveals a translationally relevant sequence of events during NAFLD progression. Cells 10 (10): 2516 (2021) (29 pp)

Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A, Trautwein C:

Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling. Nat Metab 3 (9):1228-1241 (2021)

Myllys M:

Fine tuning the gut-liver-axis. (Letter to the editor). Arch Toxicol 94: 3595-3596 (2020)

Ghallab A, Myllys M, Holland CH, Zaza A, Murad W, Hassan R, Ahmed YA, Abbas T, Abdelrahim EA, Schneider KM, Matz-Soja M, Reinders J, Gebhardt R, Berres ML, Hatting M, Drasdo D, Saez-Rodriguez J, Trautwein C, Hengstler JG:

Influence of liver fibrosis on lobular zonation. Cells 8(12): 1556 (2019) (24 pp)

Myllys M:

Highlight report: Relevance of T-cells, B-cells and immune checkpoint factors for prognosis of breast cancer. EXCLI J 18: 253-255 (2019)