Dr. Karolina Edlund

Scientific staff

Head of department
Prof. Dr. Jan G. Hengstler
Monika Turajski
Ardeystr. 67
44139 Dortmund

Here you will find the Publications from 2010 onwards that were produced at IfADo.

Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria. Cell Rep 36 (8):109526 (2021) (28 pp)
Prognostic impact of immunoglobulin kappa C (IGKC) in early breast cancer. Cancers (Basel) 13 (14): 3626 (2021) (13 pp)
Spatio-temporal multiscale analysis of western diet-fed mice reveals a translationally relevant sequence of events during NAFLD progression. Cells 10 (10): 2516 (2021) (29 pp)
Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease. Arch Toxicol 94: 205-217 (2020)
Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses. Arch Toxicol 94: 1375-1415 (2020)
HR-MAS NMR based quantitative metabolomics in breast cancer. Metabolites 9(2): E19 (2019) (27 pp)
Prognostic impact of tumor cell programmed death ligand 1 expression and immune cell infiltration in NSCLC. J Thorac Oncol 14: 628-640 (2019)
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer. Int J Cancer 145: 901-915 (2019)
Road map for development of stem cell-based alternative test methods. Trends Mol Med 25: 470-481 (2019)
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations. Arch Toxicol 93: 1609-1637 (2019)
Der Mensch zum Selberbauen? Möglichkeiten und Grenzen Stammzell-basierter Testverfahren in der Wirkstoffforschung. Laborpraxis 2019 (August): 46-49
Relevance of the incubation period in cytotoxicity testing with primary human hepatocytes. Arch Toxicol 92: 3505–3515 (2018)
Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes. Arch Toxicol 92: 3517-3533 (2018)
Impact of intratumoral heterogeneity of breast cancer tissue on quantitative metabolomics using high-resolution magic angle spinning 1 H NMR spectroscopy. NMR Biomed 31: e3862 (2018)
Metabolic profiling of ob/ob mouse fatty liver using HR-MAS 1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway. Anal Bioanal Chem 409: 1591-1606 (2017)