PD Dr. Jörg Reinders

Head of department Bioanalytics

Bioanalytics

+49 231 1084-396

reinders@ifado.de

Head of department

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

since 01/2018
Head of the Scientific Central Unit Bioanalytics (Analytical Chemistry), Leibniz Research Centre for Working Environment and Human Factors at the TU Dortmund (IfADo)
11/2013
Habilitation „Functional Genomics“, Medical Faculty, University Regensburg
04/2008 – 12/2017
Group Leader Proteomics, Institute of Functional Genomics, University Regensburg (Prof. Dr. P. J. Oefner)
10/2005 – 03/2008
Group Leader Proteomics, Julius-von-Sachs-Institute, Julius-Maximilians-University Wuerzburg (Prof. Dr. Dr. M. J. Mueller)
05/2002 – 05/2006
PhD-thesis (Dr. rer. nat.) at the Rudolf-Virchow-Center, Julius-Maximilians-University Wuerzburg (Prof. Dr. A. Sickmann)
10/1997 - 04/2002
Academic studies in biochemistry, Diploma at the Medical Proteome-Center, Ruhr-University Bochum (Prof. Dr. H. E. Meyer)

Here you will find the Publications from 2010 onwards that were produced at IfADo.

Albrecht W, Brecklinghaus T, Stolte M, Kappenberg F, Gründler L, Chen P, Cadenas C, Damm G, Edlund K, Ghallab A, Marchan R, Nell P, Reinders J, Seehofer D, Behr AC, Braeuning A, van Thriel C, Gardner I, Rahnenführer J, Hengstler JG:

Improved identification of human hepatotoxic potential by summary variables of gene expression. ALTEX. 2025. doi: 10.14573/altex.2403272. Epub ahead of print.

Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG:

Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis. J Hepatol 80: 268-281 (2024)

Gajewski PD, Rieker J, Athanassiou G, Bröde P, Claus M, Golka K, Hengstler JG, Kleinsorge T, Nitsche M, Reinders J, Tisch A, Watzl C, Wascher E, Getzmann S:

Arbeitsfähigkeit über die Lebensspanne: Rolle von biologischen, soziodemografischen, psychosozialen und Lebensstilfaktoren. In: 64. Wissenschaftliche Jahrestagung der DGAUM, 13. bis 16. März 2024 in München + online (Beitrag 17, S. 82-84). Hrsg. von Jessica Lang, Simone Schmitz-Spanke. Stuttgart: Gentner, 2024

Getzmann S, Golka K, Bröde P, Reinders J, Kadhum T, Hengstler JG, Wascher E, Gajewski PD:

Chronic Toxoplasma gondii infection modulates hearing ability across the adult life span. Life 14 (2): 194 (2024) (10 pp)

Glotzbach A, Rohlf K, Gonscharow A, Lüke S, Demirci Ö, Begher-Tibbe B, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R:

EDI3 knockdown in ER-HER2+ breast cancer cells reduces tumor burden and improves survival in two mouse models of experimental metastasis. Breast Cancer Res 26(1): 87 (2024) (20 pp)

Hassan R, Hobloss Z, Myllys M, González D, Begher-Tibbe B, Reinders J, Friebel A, Hoehme S, Abdelmageed N, Abbas AA, Seddek AL, Morad SAF, Hengstler JG, Ghallab A:

Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats. Arch Toxicol 98: 1533-1542 (2024)

Braczko F, Fischl SR, Reinders J, Lieder HR, Kleinbongard P:

Activation of the nonneuronal cholinergic cardiac system by hypoxic preconditioning protects isolated adult cardiomyocytes from hypoxia/reoxygenation injury. Am J Physiol Heart Circ Physiol 327: H70-H79 (2024)

Jürgens M, Claus M, Wingert S, Niemann JA, Picard LK, Hennes E, Haasler I, Hellwig B, Overbeck N, Reinders J, Rahnenführer J, Schedel M, Capellino S, Watzl C:

Chronic stimulation desensitizes β2-adrenergic receptor responses in natural killer cells. Eur J Immunol 54 (12): e2451299 (2024)

Kadhum T, Selinski S, Blaszkewicz M, Reinders J, Roth E, Volkert F, Ovsiannikov D, Moormann O, Gerullis H, Barski D, Otto T, Höhne S, Hengstler JG, Golka K:

Bladder cancer course, four genetic high-risk variants, and histopathological findings. EXCLI J 22: 867-879 (2023)

Larra M, Capellino S, Schwendich E, von Haugwitz L, Reinders J, Wascher E:

Immediate and delayed salivary cytokine responses during repeated exposures to Cold Pressor stress. Neuroimmunomodulation 30: 81–92 (2023)

Custodio RJP, Hobloss Z, Myllys M, Hassan R, González D, Reinders J, Bornhorst J, Weishaupt AK, Seddek AL, Abbas T, Friebel A, Hoehme S, Getzmann S, Hengstler JG, van Thriel C, Ghallab A:

Cognitive functions, neurotransmitter alterations, and hippocampal microstructural changes in mice caused by feeding on western diet. Cells 12 (18): 2331 (2023) (20 pp)

Degen GH, Reinders J, Kraft M, Völkel W, Gerull F, Burghardt R, Sievering S, Engelmann J, Chovolou Y, Hengstler JG, Fromme H:

Citrinin exposure in Germany: urine biomarker analysis in children and adults. Toxins 15: 26 (2023) (10 pp); Correction: Degen et al. Citrinin exposure in Germany: urine biomarker analysis in children and adults; Toxins 15: 26 (2023). Toxins 15 (5): 322 (2023) https://doi.org/10.3390/toxins15050322. Erratum for: Toxins (Basel) 15(1) (2023)

Gajewski PD, Rieker JA, Athanassiou G, Bröde P, Claus M, Golka K, Hengstler JG, Kleinsorge T, Nitsche MA, Reinders J, Tisch A, Watzl C, Wascher E, Getzmann S:

A systematic analysis of biological, sociodemographic, psychosocial, and lifestyle factors contributing to work ability across the working life span: cross-sectional study. JMIR Form Res 7: e40818 (2023) (25 pp)

Dichamp J, Cellière G, Ghallab A, Hassan R, Boissier N, Hofmann U, Reinders J, Sezgin S, Zühlke S, Hengstler JG, Drasdo D:

In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin. Front Bioeng Biotechnol 11: 1049564 (2023) (21 pp)

Keller M, Rohlf K, Glotzbach A, Leonhardt G, Lüke S, Derksen K, Demirci Ö, Göçener D, AlWahsh M, Lambert J, Lindskog C, Schmidt M, Brenner W, Baumann M, Zent E, Zischinsky M-L, Hellwig B, Madjar K, Rahnenführer J, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R:

Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth. J Exp Clin Cancer Res 42 (1): 25 (2023) (18 pp)