Prof. Dr. Ahmed Ghallab

Group Leader Intravital Toxicology

Head of department

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

Since 2023
Professor of Toxicology, Faculty of Veterinary Medicine, South Valley University, Egypt
Since 2021
Head of the Research Group “Intravital Toxicology”, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2018
Assistant Professor, Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, South Valley University, Egypt
2015-2021
BMBF-funded Junior Group Leader, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2013
Post-Doctoral scientist at the Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2013
Dr. med. vet., Pharmacology and Toxicology Department, Faculty of Veterinary Medicine, Justus-Liebig-University Gießen, Germany
2009
Master, Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, South Valley University, Egypt
2006
Bachelor of Veterinary Medicine, South Valley University, Egypt

Here you will find the Publications from 2010 onwards that were produced at IfADo. For all other publications of our scientific staff, please look at the links to other databases such as Pubmed.

Ghallab A, Cellière G, Henkel SG, Driesch D, Hoehme S, Hofmann U, Zellmer S, Godoy P, Sachinidis A, Blaszkewicz M, Reif R, Marchan R, Kuepfer L, Häussinger D, Drasdo D, Gebhardt R, Hengstler JG:

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. J Hepatol 64: 860–871 (2016)

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG:

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch Toxicol 90: 2513-2529 (2016)

Ghallab A:

Highlight report: Blueprint for stem cell differentiation into liver cells. EXCLI J 14: 1017-1019 (2015)

Ghallab A:

Highlight report: Acetaminophen hepatotoxicity. Arch Toxicol 89: 2449-2451 (2015)

Ghallab A:

Interspecies extrapolation by physiologically based pharmacokinetic modeling (Guest editorial). EXCLI J 14: 1261-1263 (2015)

Ghallab A:

Highlight report: New methods for quantification of bile canalicular dynamics (Guest editorial). EXCLI J 14: 1264-1266 (2015)

Ghallab A:

Systems Toxicology (Guest editorial). EXCLI J 14: 1267-1269 (2015)

Thiel C, Schneckener S, Krauss M, Ghallab A, Hofmann U, Kanacher T, Zellmer S, Gebhardt R, Hengstler JG, Kuepfer L:

A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation. J Pharm Sci 104: 191-206 (2015)

Bartl M, Pfaff M, Ghallab A, Driesch D, Henkel SG, Hengstler JG, Schuster S, Kaleta C, Gebhardt R, Zellmer S, Li P:

Optimality in the zonation of ammonia detoxification in rodent liver. Arch Toxicol 89: 2069-2078 (2015)

Ghallab A:

Highlight report: Perspectives in stem cell research - unbiased quantification of the similarity between in vitro generated and primary hepatocytes. (Editorial). Arch Toxicol 89: 2185-2187 (2015)

Ghallab A:

Highlight report: Role of the circadian clock system in breast cancer. EXCLI J 14: 540-541 (2015)

Hengstler JG, Hammad S, Ghallab A, Reif R, Godoy P:

In vitro systems for hepatoxicity testing. In: Bal-Price A, Jennings P (eds.): In vitro toxicology systems. Methods in pharmacology and toxicology (pp 27-44). New York: Springer Science+Business Media, 2014

Campos G, Schmidt-Heck W, Ghallab A, Rochlitz K, Pütter L, Medinas DB, Hetz C, Widera A, Cadenas C, Begher-Tibbe B, Reif R, Günther G, Sachinidis A, Hengstler JG, Godoy P:

The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity. Arch Toxicol 88: 1267-1280 (2014)

Ghallab A:

Highlights in tumor metabolome research: choline metabolism influences integrin expression and supports cell attachment. (Letter to the editor). EXCLI J 13: 856-858 (2014)

Ghallab A:

Perspectives in toxicologic pathology: quantification of bile canalicular networks. (Letter to the editor). Arch Toxicol 88: 1907-1908 (2014)