Prof. Dr. Ahmed Ghallab

Group Leader Intravital Toxicology

Head of department

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

Since 2023
Professor of Toxicology, Faculty of Veterinary Medicine, South Valley University, Egypt
Since 2021
Head of the Research Group “Intravital Toxicology”, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2018
Assistant Professor, Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, South Valley University, Egypt
2015-2021
BMBF-funded Junior Group Leader, Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2013
Post-Doctoral scientist at the Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany
2013
Dr. med. vet., Pharmacology and Toxicology Department, Faculty of Veterinary Medicine, Justus-Liebig-University Gießen, Germany
2009
Master, Forensic Medicine and Toxicology Department, Faculty of Veterinary Medicine, South Valley University, Egypt
2006
Bachelor of Veterinary Medicine, South Valley University, Egypt

Here you will find the Publications from 2010 onwards that were produced at IfADo. For all other publications of our scientific staff, please look at the links to other databases such as Pubmed.

Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek A-l, Marchan R, Cramer B, Humpf H-U, Hoehme S, Degen GH, Hengstler JG, Ghallab A:

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Arch Toxicol 96: 3349–3361 (2022)

Kube I, Kowalczyk M, Hofmann U, Ghallab A, Hengstler JG, Führer D, Zwanziger D:

Hepatobiliary thyroid hormone deficiency impacts bile acid hydrophilicity and aquaporins in cholestatic C57BL/6J mice. Int J Mol Sci 23 (20): 12355 (2022) (15 pp)

Wehling L, Keegan L, Fernández-Palanca P, Hassan R, Ghallab A, Schmitt J, Tang Y, Le Marois M, Roessler S, Schirmacher P, Kummer U, Hengstler JG, Sahle S, Breuhahn K:

Spatial modeling reveals nuclear phosphorylation and subcellular shuttling of YAP upon drug-induced liver injury. Elife 11: e78540 (2022) (28 pp)

Hassan R, Myllys M, Brackhagen L, Hobloss Z, González D, Seddek A-L, Friebel A, Hoehme S, Marchan R, Trauner M, Hengstler JG, Ghallab A:

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins. Arch Toxicol 96: 3067-3076 (2022)

Schuran FA, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, Zuehlke S, Reinders J, Heeren J, Lohse AW, Schramm C, Herkel J, Carambia A:

Aryl hydrocarbon receptor activity in hepatocytes sensitizes to hyperacute acetaminophen-induced hepatotoxicity in mice. Cell Mol Gastroenterol Hepatol 11: 371-388 (2021)

Gupta R, Schrooders Y, Hauser D, van Herwijnen M, Albrecht W, Ter Braak B, Brecklinghaus T, Castell JV, Elenschneider L, Escher S, Guye P, Hengstler JG, Ghallab A, Hansen T, Leist M, Maclennan R, Moritz W, Tolosa L, Tricot T, Verfaillie C, Walker P, van de Water B, Kleinjans J, Caiment F:

Comparing in vitro human liver models to in vivo human liver using RNA-Seq. Arch Toxicol 95: 573–589 (2021)

Schneider KM, Elfers C, Ghallab A, Schneider CV, Galvez EJC, Mohs A, Gui W, Candels LS, Wirtz TH, Zuehlke S, Spiteller M, Myllys M, Roulet A, Ouzerdine A, Lelouvier B, Kilic K, Liao L, Nier A, Latz E, Bergheim I, Thaiss CA, Hengstler JG, Strowig T, Trautwein C:

Intestinal dysbiosis amplifies acetaminophen-induced acute liver injury. Cell Mol Gastroenterol Hepatol 11: 909-933 (2021)

Vartak N, Guenther G, Joly F, Damle‐Vartak A, Wibbelt G, Fickel J, Jörs S, Begher‐Tibbe B, Friebel A, Wansing K, Ghallab A, Rosselin R, Boissier N, Vignon‐Clementel I, Hedberg C, Geisler F, Hofer H, Hoehme S, Drasdo D, Hengstler JG:

Intravital dynamic and correlative imaging of mouse livers reveals diffusion-dominated canalicular and flow-augmented ductular bile flux. Hepatology 73: 1531-1550 (2021)

Ghallab A, Hassan R, Myllys M, Albrecht W, Friebel A, Hoehme S, Hofmann U, Seddek AL, Braeuning A, Kuepfer L, Cramer B, Humpf HU, Boor P, Degen GH, Hengstler JG:

Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney. Arch Toxicol 95: 2163-2177 (2021)

Kube I, Tardio LB, Hofmann U, Ghallab A, Hengstler JG, Fuehrer D, Zwanziger D:

Hypothyroidism increases cholesterol gallstone prevalence in mice by elevated hydrophobicity of primary bile acids. Thyroid 31: 973–984 (2021)