Publications Toxicology

Huang X, Nussler AK, Reumann MK, Augat P, Menger MM, Ghallab A, Hengstler JG, Histing T, Ehnert S:

Contribution to the 3R principle: description of a specimen-specific finite element model simulating 3-point-bending tests in mouse tibiae. Bioengineering (Basel) 9(8): 337 (2022) (9 pp)

Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG:

In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay. Toxicol Lett 368: 33-46 (2022)

Almstedt K, Heimes AS, Kappenberg F, Battista MJ, Lehr HA, Krajnak S, Lebrecht A, Gehrmann M, Stewen K, Brenner W, Weikel W, Rahnenführer J, Hengstler JG, Hasenburg A, Schmidt M:

Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer. Eur J Cancer 173: 10-19 (2022)

Böthig R, Rosenbaum C, Böhme H, Kowald B, Fiebag K, Thietje R, Schöps W, Kadhum T, Golka K:

Special surgical aspects of radical cystectomy in spinal cord injury patients with bladder cancer. World J Urol 40: 1961–1970 (2022)

Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Jäger H, Joost HG, Kulling S, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Vieths S, Wätjen W, Steinberg P:

Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis. (Guest editorial). Arch Toxicol 96: 1905-1914 (2022)

Cherianidou A, Seidel F, Kappenberg F, Dreser N, Blum J, Waldmann T, Blüthgen N, Meisig J, Madjar K, Henry M, Rotshteyn T, Marchan R, Edlund K, Leist M, Rahnenführer J, Sachinidis A, Hengstler JG:

Classification of developmental toxicants in a human iPSC transcriptomics-based test. Chem Res Toxicol 35: 760–773 (2022)

Kyei NNA, Cramer B, Humpf HU, Degen GH, Ali N, Gabrysch S:

Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh. Arch Toxicol 96: 2123–2138 (2022)

Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG:

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity. J Hepatol 77: 71-83 (2022)

Salehinejad MA, Ghanavati E, Reinders J, Hengstler JG, Kuo M-F, Nitsche MA:

Sleep-dependent upscaled excitability, saturated neuroplasticity, and modulated cognition in the human brain. eLife 11: e69308 (2022) (33 pp)

Röhl C, Batke M, Damm G, Freyberger A, Gebel T, Gundert-Remy U, Hengstler JG, Mangerich A, Matthiessen A, Partosch F, Schupp T, Wollin KM, Foth H:

New aspects in deriving health-based guidance values for bromate in swimming pool water. Arch Toxicol 96: 1623-1659 (2022)

Yu EY, Stern MC, Jiang X, Tang L, van den Brandt PA, Lu CM, Karagas MR, La Vecchia C, Bosetti C, Polesel J, Golka K, Zhang ZF, Villeneuve P, Zeegers MP, Wesselius A:

Family history and risk of bladder cancer: an analysis accounting for first- and second-degree relatives. Cancer Prev Res 15: 319-326 (2022)

Elberskirch L, Sofranko A, Liebing J, Riefler N, Binder K, Bonatto Minella C, Razum M, Mädler L, Unfried K, Schins RPF, Kraegeloh A, van Thriel C:

How structured metadata acquisition contributes to the reproducibility of nanosafety studies: evaluation by a round-robin test. Nanomaterials (Basel) 12 (7): 1053 (2022) (20 pp)

Rietjens IMCM, Arand M, Bolt HM, Bourdoux S, Hartwig A, Hinrichsen N, Kalisch C, Mally A, Pellegrino G, Ribera D, Thatcher N, Eisenbrand G:

The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment. Arch Toxicol 96: 1297–1352 (2022)

Brecklinghaus T, Albrecht W, Kappenberg F, Duda J, Zhang M, Gardner I, Marchan R, Ghallab A, Turgunbayer ÖD, Rahnenführer J, Hengstler JG:

Influence of bile acids on the cytotoxicity of chemicals in cultivated human hepatocytes. Toxicol In Vitro 81: 105344 (2022)

Remetic J, Ghallab A, Hobloss Z, Brackhagen L, Hassan R, Myllys M, Radun R, Mlitz V, Zhu C, Baumgartner M, Schrottmaier WC, Mussbacher M, Timelthaler G, Scharnagl H, Stojakovic T, Assinger A, Fuchs CD, Hengstler JG, Trauner M:

Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance. Hepatology 75: 1095-1109 (2022)