Publications Toxicology

Gui W, Hole MJ, Molinaro A, Edlund K, Jørgensen KK, Su H, Begher-Tibbe B, Gaßler N, Schneider CV, Muthukumarasamy U, Mohs A, Liao L, Jaeger J, Mertens CJ, Bergheim I, Strowig T, Hengstler JG, Hov JR, Marschall HU, Trautwein C, Schneider KM:

Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis. Nat Commun 14 (1): 3304 (2023) (17 pp)

Gajewski PD, Golka K, Hengstler JG, Kadhum T, Digutsch J, Genç E, Wascher E, Getzmann S:

Does physical fitness affect cognitive functions differently across adulthood? An advantage of being older. Front Psychol 14: 1134770 (2023) (14 pp)

van Thriel C, Monsé C, Rettenmeier AW, Sucker K, Werner S, Leibold E, Brüning T, Arand M, Käfferlein H, Bartsch R, Kreis P, Hartwig A, MAK Commission:

Geruchsintensive Stoffe: Grundlagen, Bewertung und Markierung. MAK-Begründung. MAK Collect Occup Health Saf 8 (1): Doc010 (2023) (15 pp)

Vignon-Clementel IE, Jagiella N, Dichamp J, Kowalski J, Lederle W, Laue H, Kiessling F, Sedlaczek O, Drasdo D:

A proof-of-concept pipeline to guide evaluation of tumor tissue perfusion by dynamic contrast-agent imaging: Direct simulation and inverse tracer-kinetic procedures. Front Bioinform 3: 977228 (2023) (19 pp)

Gajewski PD, Rieker JA, Athanassiou G, Bröde P, Claus M, Golka K, Hengstler JG, Kleinsorge T, Nitsche MA, Reinders J, Tisch A, Watzl C, Wascher E, Getzmann S:

A systematic analysis of biological, sociodemographic, psychosocial, and lifestyle factors contributing to work ability across the working life span: cross-sectional study. JMIR Form Res 7: e40818 (2023) (25 pp)

Martínez-Sena T, Moro E, Moreno-Torres M, Quintás G, Hengstler J, Castell JV:

Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved. Arch Toxicol 97: 1723-1738 (2023)

Lehmann A, Geburek I, These A, Hessel-Pras S, Hengstler JG, Albrecht W, Mielke H, Müller-Graf C, Yang X, Kloft C, Hethey C:

PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat. Arch Toxicol 97: 1319–1333 (2023)

Keller M, Rohlf K, Glotzbach A, Leonhardt G, Lüke S, Derksen K, Demirci Ö, Göçener D, AlWahsh M, Lambert J, Lindskog C, Schmidt M, Brenner W, Baumann M, Zent E, Zischinsky M-L, Hellwig B, Madjar K, Rahnenführer J, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R:

Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth. J Exp Clin Cancer Res 42 (1): 25 (2023) (18 pp)

Hoehme S, Hammad S, Boettger J, Begher-Tibbe B, Bucur P, Vibert E, Gebhardt R, Hengstler JG, Drasdo D:

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy. iScience 26 (1):105714 (2023) (34 pp)

Guth S, Baum M, Cartus AT, Diel P, Engel K-H, Engeli B, Epe B, Grune T, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf H-U, Jäger H, Joost H-G, Kulling SE, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Steinberg P, Vieths S, Wätjen W, Eisenbrand G:

Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value). Food Chem Toxicol 173: 113632 (2023) (13 pp)

Hucke CI, Heinen RM, Wascher E, van Thriel C:

Trigeminal stimulation is required for neural representations of bimodal odor localization: A time-resolved multivariate EEG and fNIRS study. Neuroimage 269: 119903 (11 pp) (2023)

Zang JCS, May C, Hellwig B, Moser D, Hengstler JG, Cole S, Heinrichs M, Rahnenführer J, Marcus K, Kumsta R:

Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences. Transl Psychiatry 13 (1): 31 (2023) (12 pp)

Dichamp J, Cellière G, Ghallab A, Hassan R, Boissier N, Hofmann U, Reinders J, Sezgin S, Zühlke S, Hengstler JG, Drasdo D:

In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin. Front Bioeng Biotechnol 11: 1049564 (2023) (21 pp)

Almstedt K, Krauthauser L, Kappenberg F, Wagner D-C, Heimes A-S, Battista MJ, Anic K, Krajnak S, Lebrecht A, Schwab R, Brenner W, Weikel W, Rahnenführer J, Hengstler JG, Roth W, Hasenburg A, Stewen K, Schmidt M:

Discordance of HER2-low between primary tumors and matched distant metastases in breast cancer. Cancers (Basel) 15 (5): 1413 (2023) (15 pp)

Rieker JA, Gajewski PD, Reales JM, Ballesteros S, Golka K, Hengstler JG, Wascher E, Getzmann S:

The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults. Int Arch Occup Environ Health 96: 507–520 (2023)