Publications Toxicology

Friebel A, Johann T, Drasdo D, Hoehme S:

Guided interactive image segmentation using machine learning and color-based image set clustering. Bioinformatics 38: 4622–4628 (2022) (7 pp)

Nell P, Kattler K, Feuerborn D, Hellwig B, Rieck A, Salhab A, Lepikhov K, Gasparoni G, Thomitzek A, Belgasmi K, Blüthgen N, Morkel M, Küppers-Munther B, Godoy P, Hay DC, Cadenas C, Marchan R, Vartak N, Edlund K, Rahnenführer J, Walter J, Hengstler JG:

Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells. J Hepatol 77: 1386-1398 (2022)

Mattonet K, Nowack-Weyers N, Vogel V, Moser D, Tierling S, Kasper-Sonnenberg M, Wilhelm M, Scherer M, Walter J, Hengstler JG, Schölmerich A, Kumsta R:

Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood. Epigenetics 17: 935-952 (2022)

Wijaya LS, Rau C, Braun TS, Marangoz S, Spegg V, Vlasveld M, Albrecht W, Brecklinghaus T, Kamp H, Beltman JB, Hengstler JG, van de Water B, Leist M, Schildknecht S:

Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes. Cell Biol Toxicol 38: 847-864 (2022)

Jungmann O, Böthig R, Buntrock S, Habelt C, Kaufmann A, Nieder P, Proff U, Scherhag N, Stahl L, Woltjen M, Zellner M, Schöps W, Golka K:

Nierenverlust. In: Ludoph E, Schürmann J, Gaidzik PW (Hrsg.): Kursbuch der ärztlichen Begutachtung. Handbuch (Kap. VI-8.2.1, 67. Erg.-Lfg. 8/22, S. 1-10). Landsberg/Lech: Ecomed Medizin, 2022

Alimba CG, Sivanesan S, Krishnamurthi K:

Mitochondrial dysfunctions elicited by solid waste leachates provide insights into mechanisms of leachates induced cell death and pathophysiological disorders. Chemosphere 307 (4): 136085 (2022)

Huang X, Nussler AK, Reumann MK, Augat P, Menger MM, Ghallab A, Hengstler JG, Histing T, Ehnert S:

Contribution to the 3R principle: description of a specimen-specific finite element model simulating 3-point-bending tests in mouse tibiae. Bioengineering (Basel) 9(8): 337 (2022) (9 pp)

Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG:

In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay. Toxicol Lett 368: 33-46 (2022)

Almstedt K, Heimes AS, Kappenberg F, Battista MJ, Lehr HA, Krajnak S, Lebrecht A, Gehrmann M, Stewen K, Brenner W, Weikel W, Rahnenführer J, Hengstler JG, Hasenburg A, Schmidt M:

Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer. Eur J Cancer 173: 10-19 (2022)

Böthig R, Rosenbaum C, Böhme H, Kowald B, Fiebag K, Thietje R, Schöps W, Kadhum T, Golka K:

Special surgical aspects of radical cystectomy in spinal cord injury patients with bladder cancer. World J Urol 40: 1961–1970 (2022)

Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Jäger H, Joost HG, Kulling S, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Vieths S, Wätjen W, Steinberg P:

Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis. (Guest editorial). Arch Toxicol 96: 1905-1914 (2022)

Cherianidou A, Seidel F, Kappenberg F, Dreser N, Blum J, Waldmann T, Blüthgen N, Meisig J, Madjar K, Henry M, Rotshteyn T, Marchan R, Edlund K, Leist M, Rahnenführer J, Sachinidis A, Hengstler JG:

Classification of developmental toxicants in a human iPSC transcriptomics-based test. Chem Res Toxicol 35: 760–773 (2022)

Kyei NNA, Cramer B, Humpf HU, Degen GH, Ali N, Gabrysch S:

Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh. Arch Toxicol 96: 2123–2138 (2022)

Ghallab A, Hassan R, Hofmann U, Friebel A, Hobloss Z, Brackhagen L, Begher-Tibbe B, Myllys M, Reinders J, Overbeck N, Sezgin S, Zühlke S, Seddek AL, Murad W, Brecklinghaus T, Kappenberg F, Rahnenführer J, González D, Goldring C, Copple IM, Marchan R, Longerich T, Vucur M, Luedde T, Urban S, Canbay A, Schreiter T, Trauner M, Akakpo JY, Olyaee M, Curry SC, Sowa JP, Jaeschke H, Hoehme S, Hengstler JG:

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity. J Hepatol 77: 71-83 (2022)

Salehinejad MA, Ghanavati E, Reinders J, Hengstler JG, Kuo M-F, Nitsche MA:

Sleep-dependent upscaled excitability, saturated neuroplasticity, and modulated cognition in the human brain. eLife 11: e69308 (2022) (33 pp)