Publications Toxicology

Lehmann A, Geburek I, These A, Hessel-Pras S, Hengstler JG, Albrecht W, Mielke H, Müller-Graf C, Yang X, Kloft C, Hethey C:

PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat. Arch Toxicol 97: 1319–1333 (2023)

Keller M, Rohlf K, Glotzbach A, Leonhardt G, Lüke S, Derksen K, Demirci Ö, Göçener D, AlWahsh M, Lambert J, Lindskog C, Schmidt M, Brenner W, Baumann M, Zent E, Zischinsky M-L, Hellwig B, Madjar K, Rahnenführer J, Overbeck N, Reinders J, Cadenas C, Hengstler JG, Edlund K, Marchan R:

Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth. J Exp Clin Cancer Res 42 (1): 25 (2023) (18 pp)

Hoehme S, Hammad S, Boettger J, Begher-Tibbe B, Bucur P, Vibert E, Gebhardt R, Hengstler JG, Drasdo D:

Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy. iScience 26 (1):105714 (2023) (34 pp)

Guth S, Baum M, Cartus AT, Diel P, Engel K-H, Engeli B, Epe B, Grune T, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf H-U, Jäger H, Joost H-G, Kulling SE, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Steinberg P, Vieths S, Wätjen W, Eisenbrand G:

Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value). Food Chem Toxicol 173: 113632 (2023) (13 pp)

Hucke CI, Heinen RM, Wascher E, van Thriel C:

Trigeminal stimulation is required for neural representations of bimodal odor localization: A time-resolved multivariate EEG and fNIRS study. Neuroimage 269: 119903 (11 pp) (2023)

Zang JCS, May C, Hellwig B, Moser D, Hengstler JG, Cole S, Heinrichs M, Rahnenführer J, Marcus K, Kumsta R:

Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences. Transl Psychiatry 13 (1): 31 (2023) (12 pp)

Dichamp J, Cellière G, Ghallab A, Hassan R, Boissier N, Hofmann U, Reinders J, Sezgin S, Zühlke S, Hengstler JG, Drasdo D:

In vitro to in vivo acetaminophen hepatotoxicity extrapolation using classical schemes, pharmacodynamic models and a multiscale spatial-temporal liver twin. Front Bioeng Biotechnol 11: 1049564 (2023) (21 pp)

Almstedt K, Krauthauser L, Kappenberg F, Wagner D-C, Heimes A-S, Battista MJ, Anic K, Krajnak S, Lebrecht A, Schwab R, Brenner W, Weikel W, Rahnenführer J, Hengstler JG, Roth W, Hasenburg A, Stewen K, Schmidt M:

Discordance of HER2-low between primary tumors and matched distant metastases in breast cancer. Cancers (Basel) 15 (5): 1413 (2023) (15 pp)

Rieker JA, Gajewski PD, Reales JM, Ballesteros S, Golka K, Hengstler JG, Wascher E, Getzmann S:

The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults. Int Arch Occup Environ Health 96: 507–520 (2023)

Deutsche Krebsgesellschaft (Mitarb. u.a.:

Golka, K.): Leitlinienprogramm Onkologie. S3-Leitlinie Diagnostik, Therapie und Nachsorge des Nierenzellkarzinoms, Langversion 4.0 – Februar 2023 AWMF-Registernummer: 043-017OL (294 S.) Berlin: Office des Leitlinienprogrammes Onkologie, 2023

Deutsche Krebsgesellschaft (Mitarb. u.a.:

Golka, K.): Leitlinienprogramm Onkologie. S3 - Leitlinie Diagnostik, Therapie und Nachsorge des Nierenzellkarzinoms, Kurzversion 4.0 – Februar 2023 AWMF-Registernummer: 043-017OL (89 S.). Berlin: Office des Leitlinienprogrammes Onkologie, 2023

EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings), (u. a. Degen, G.):

Flavouring Group Evaluation 21 Revision 6 (FGE.21Rev6): thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30. EFSA Journal 21 (2): 7777 (2023) (66 pp)

EFSA FAF Panel (EFSA Panel on Food Additives and Flavourings), (u. a. Degen, G.):

Re-evaluation of locust bean gum (E 410) as a food additive in foods for infants below 16 weeks of age and follow-up of its re-evaluation as a food additive for uses in foods for all population groups. EFSA Journal 21 (2): 7775 (2023) (70 pp)

Akan O, Bierbrauer A, Kunz L, Gajewski PD, Getzmann S, Hengstler JG, Wascher E, Axmacher N, Wolf OT:

Chronic stress is associated with specific path integration deficits. Behav Brain Res 442: 114305 (2023) (13 pp)

Degen GH, Reinders J, Kraft M, Völkel W, Gerull F, Burghardt R, Sievering S, Engelmann J, Chovolou Y, Hengstler JG, Fromme H:

Citrinin exposure in Germany: urine biomarker analysis in children and adults. Toxins 15: 26 (2023) (10 pp); Correction: Degen et al. Citrinin exposure in Germany: urine biomarker analysis in children and adults; Toxins 15: 26 (2023). Toxins 15 (5): 322 (2023) https://doi.org/10.3390/toxins15050322. Erratum for: Toxins (Basel) 15(1) (2023)