Publications Toxicology

Hassan R, González D, Hobloss Z, Brackhagen L, Myllys M, Friebel A, Seddek A-l, Marchan R, Cramer B, Humpf H-U, Hoehme S, Degen GH, Hengstler JG, Ghallab A:

Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A. Arch Toxicol 96: 3349–3361 (2022)

Hassan R, Friebel A, Brackhagen L, Hobloss Z, Myllys M, González D, Albrecht W, Mohammed ESI, Seddek A-L, Marchan R, Cadenas C, Cramer B, Humpf H-U, Hartl L, Simbrunner B, Reiberger T, Trauner M, Hoehme S, Degen GH, Hengstler JG, Ghallab A:

Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity. Arch Toxicol 96: 2967–2981 (2022)

Friebel A, Johann T, Drasdo D, Hoehme S:

Guided interactive image segmentation using machine learning and color-based image set clustering. Bioinformatics 38: 4622–4628 (2022) (7 pp)

Nell P, Kattler K, Feuerborn D, Hellwig B, Rieck A, Salhab A, Lepikhov K, Gasparoni G, Thomitzek A, Belgasmi K, Blüthgen N, Morkel M, Küppers-Munther B, Godoy P, Hay DC, Cadenas C, Marchan R, Vartak N, Edlund K, Rahnenführer J, Walter J, Hengstler JG:

Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells. J Hepatol 77: 1386-1398 (2022)

Mattonet K, Nowack-Weyers N, Vogel V, Moser D, Tierling S, Kasper-Sonnenberg M, Wilhelm M, Scherer M, Walter J, Hengstler JG, Schölmerich A, Kumsta R:

Prenatal exposure to endocrine disrupting chemicals is associated with altered DNA methylation in cord blood. Epigenetics 17: 935-952 (2022)

Wijaya LS, Rau C, Braun TS, Marangoz S, Spegg V, Vlasveld M, Albrecht W, Brecklinghaus T, Kamp H, Beltman JB, Hengstler JG, van de Water B, Leist M, Schildknecht S:

Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes. Cell Biol Toxicol 38: 847-864 (2022)

Jungmann O, Böthig R, Buntrock S, Habelt C, Kaufmann A, Nieder P, Proff U, Scherhag N, Stahl L, Woltjen M, Zellner M, Schöps W, Golka K:

Nierenverlust. In: Ludoph E, Schürmann J, Gaidzik PW (Hrsg.): Kursbuch der ärztlichen Begutachtung. Handbuch (Kap. VI-8.2.1, 67. Erg.-Lfg. 8/22, S. 1-10). Landsberg/Lech: Ecomed Medizin, 2022

Alimba CG, Sivanesan S, Krishnamurthi K:

Mitochondrial dysfunctions elicited by solid waste leachates provide insights into mechanisms of leachates induced cell death and pathophysiological disorders. Chemosphere 307 (4): 136085 (2022)

Huang X, Nussler AK, Reumann MK, Augat P, Menger MM, Ghallab A, Hengstler JG, Histing T, Ehnert S:

Contribution to the 3R principle: description of a specimen-specific finite element model simulating 3-point-bending tests in mouse tibiae. Bioengineering (Basel) 9(8): 337 (2022) (9 pp)

Brecklinghaus T, Albrecht W, Duda J, Kappenberg F, Gründler L, Edlund K, Marchan R, Ghallab A, Cadenas C, Rieck A, Vartak N, Tolosa L, Castell JV, Gardner I, Halilbasic E, Trauner M, Ullrich A, Zeigerer A, Demirci Turgunbayer Ö, Damm G, Seehofer D, Rahnenführer J, Hengstler JG:

In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay. Toxicol Lett 368: 33-46 (2022)

Almstedt K, Heimes AS, Kappenberg F, Battista MJ, Lehr HA, Krajnak S, Lebrecht A, Gehrmann M, Stewen K, Brenner W, Weikel W, Rahnenführer J, Hengstler JG, Hasenburg A, Schmidt M:

Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer. Eur J Cancer 173: 10-19 (2022)

Wishahi M, Otto T, Golka K:

Re: bladder carcinomas in patients with neurogenic bladder and urinary schistosomiasis-are they the same tumors? (Letter to the editor). World J Urol 40: 2139–2140 (2022)

Böthig R, Rosenbaum C, Böhme H, Kowald B, Fiebag K, Thietje R, Schöps W, Kadhum T, Golka K:

Special surgical aspects of radical cystectomy in spinal cord injury patients with bladder cancer. World J Urol 40: 1961–1970 (2022)

Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Jäger H, Joost HG, Kulling S, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Vieths S, Wätjen W, Steinberg P:

Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis. (Guest editorial). Arch Toxicol 96: 1905-1914 (2022)

Cherianidou A, Seidel F, Kappenberg F, Dreser N, Blum J, Waldmann T, Blüthgen N, Meisig J, Madjar K, Henry M, Rotshteyn T, Marchan R, Edlund K, Leist M, Rahnenführer J, Sachinidis A, Hengstler JG:

Classification of developmental toxicants in a human iPSC transcriptomics-based test. Chem Res Toxicol 35: 760–773 (2022)