The task of the Bioanalytics Unit is to support the project groups in all questions regarding qualitative and quantitative analysis at the molecular level. In cooperation with the various project groups, the required analysis protocols are developed and established and the measurements are carried out. Many different levels of omics-based science are used, such as proteomics, metabolomics and lipidomics, in order to obtain the most comprehensive overview possible of the molecular changes caused by different diseases, treatments or other internal and external stimuli.
For this purpose, mainly chromatography-coupled mass spectrometry methods are used, which enable both the targeted highly sensitive quantification of known analytes and the identification and quantification of previously unknown target molecules. In addition, high-throughput methods for the determination of inflammatory factors and biogenic amines are also established and provided for the Institute's project groups. Furthermore, technical support is also provided, e.g. in the control and monitoring of exposure experiments with volunteers for the other working groups.