Dr. Raly James Perez Custodio

Scientific staff

Aging

+49 231 1084-369

custodio@ifado.de

Head of department

Prof. Dr. Edmund Wascher

wascher@ifado.de

+49 231 1084-362

Secretariat

Judith Geiger

geiger@ifado.de

+49 231 1084-361

Address

Ardeystr. 67
44139 Dortmund

since 06/2022
Post-doctoral Researcher, Ergonomics Department, Leibniz Research Centre for Working Environment and Human Factors (IfADo)
09/2021-05/2022
Post-doctoral Researcher, Institute for New Drug Development, College of Pharmacy, Jeonbuk National University, Jeonju, South Korea
08/2021
Doctor of Philosophy (Ph.D.) in Pharmacy (major in Pharmacology), Graduate School of Pharmacy, Sahmyook University, Seoul, South Korea
08/2018
Master of Science (M.Sc.) in Pharmacy (major in Pharmacology), Graduate School of Pharmacy, Sahmyook University, Seoul, South Korea
08/2016-08/2021
Graduate Researcher, Uimyung Research Institute for Neuroscience, Laboratory of Pharmacology, Sahmyook University, Seoul, South Korea
10/2015
Master of Arts (M.A.) in Nursing major in Clinical Supervision at the School of Healthcare Professions, Department of Nursing, University of San Carlos, Cebu City, Philippines
03/2014-07/2016
Clinical Instructor (General and Psychiatric Nursing), College of Nursing, Colegio de Sta. Lourdes of Leyte foundation, Inc., Tabontabon, Leyte, Philippines
01/2014
Registered Nurse (R.N.) in the Philippines
05/2013
Bachelor of Science (B.Sc.) in Nursing, College of Nursing, Colegio de Sta. Lourdes of Leyte Foundation, Inc., Tabontabon, Leyte, Philippines

Here you will find the Publications from 2010 onwards that were produced at IfADo.

Custodio RJP, Sayson LV, Cho A, Jung H, Ortiz DM, Lee HJ, Alyan E, Wascher E, Getzmann S, Kim M, Kim KM, Yi EC, Kim HJ, Cheong JH:

Unraveling Predominantly Inattentive ADHD (ADHD-PI): Insights from Proteomic Analysis of the Striatum of Thyroid Hormone-Responsive Protein (THRSP)-Overexpressing Mice. Mol Neurobiol (2025) doi: 10.1007/s12035-025-05031-z. Epub ahead of print.

Custodio RJP, Ortiz DM, Lee HJ, Sayson LV, Kim M, Lee YS, Kim KM, Cheong JH, Kim HJ:

Serotonin 2C receptors are also important in head-twitch responses in male mice. Psychopharmacology (Berl) 242(7): 1585-1605 (epub 2023, print 2025) doi: 10.1007/s00213-023-06482-9.

Bormate KJ, Lee BK, Kim T-H, Custodio RJP, Cheong JH, Kim HJ, Shim SH, Pil GB, Kim HJ, Son RH, Yeon SH, Park JW, Lee C-K, Jung Y-S:

Involvement of adenosine A1 receptor in the sleep-promoting effect of fermented Perilla frutescens. J Funct Foods 120: 106345 (2024) doi:10.1016/j.jff.2024.106345

Custodio RJP, Hengstler JG, Cheong JH, Kim HJ, Wascher E, Getzmann S:

Adult ADHD: it is old and new at the same time - what is it? Rev Neurosci 35: 225–241 (2024)

Custodio RJP, Hobloss Z, Myllys M, Hassan R, González D, Reinders J, Bornhorst J, Weishaupt AK, Seddek AL, Abbas T, Friebel A, Hoehme S, Getzmann S, Hengstler JG, van Thriel C, Ghallab A:

Cognitive functions, neurotransmitter alterations, and hippocampal microstructural changes in mice caused by feeding on western diet. Cells 12 (18): 2331 (2023) (20 pp)

Custodio RJP, Kim HJ, Kim J, Ortiz DM, Kim M, Buctot D, Sayson LV, Lee HJ, Kim BN, Yi EC, Cheong JH:

Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model. Commun Biol 6(1): 55 (2023)

Sayson LV, Ortiz DM, Lee HJ, Kim M, Custodio RJP, Yun J, Lee CH, Lee YS, Cha HJ, Cheong JH, Kim HJ:

Deletion of Cryab increases the vulnerability of mice to the addiction-like effects of the cannabinoid JWH-018 via upregulation of striatal NF-κB expression. Front Pharmacol 14: 1135929 (2023) (19 pp)

Ortiz DMD, Kim M, Lee HJ, Botanas CJ, Custodio RJP, Sayson LV, Campomayor NB, Lee C, Lee YS, Cheong JH, Kim HJ:

4-F-PCP, a novel PCP analog ameliorates the depressive-like behavior of chronic social defeat stress mice via NMDA receptor antagonism. Biomol Ther (Seoul) 31: 227-239 (2023)

Sayson LV, Lee HJ, Ortiz DM, Kim M, Custodio RJP, Lee CH, Lee YS, Cheong JH, Kim HJ:

The differential vulnerabilities of Per2 knockout mice to the addictive properties of methamphetamine and cocaine. Prog Neuropsychopharmacol Biol Psychiatry 126: 110782 (2023)

Custodio RJP, Kim M, Chung YC, Kim BN, Kim HJ, Cheong JH:

Thrsp gene and the ADHD predominantly inattentive presentation. ACS Chem Neurosci 14: 573-589 (2023)