Publikationen Toxikologie

Brandt A, Yergaliyev T, Halibasic E, Cyba A, Jaeger J, Gong R, Hernández-Arriaga A, Schneider CV, Sjöland W, Molinaro A, Trauner M, Trautwein C, Camarinha-Silva A, Bergheim I, Schneider KM:

Fiber enrichment is not superior to dietary monitoring in MASLD: A dual-center, double-blind, placebo-controlled trial. iScience 28(12): 114019 (2025) doi: 10.1016/j.isci.2025.114019

Engler R, Stammen C, Arnau S, Schneider Penate J, Metzen D, Digutsch J, Gajewski PD, Getzmann S, Fraenz C, Reinders J, Voelkle MC, Streit F, Ocklenburg S, Schneider D, Burke M, Hengstler JG, Watzl C, Nitsche MA, Kumsta R, Wascher E, Genç E:

Electrophysiological resting-state signatures link polygenic scores to general intelligence. Sci Rep 15(1): 41170 (2025) doi: 10.1038/s41598-025-26778-4

Goldring CE, Russomanno G, Pin C, Trairatphisan P, Beattie KA, Fisher CP, Piñero J, Brennan RJ, Clausznitzer D, Copple IM, de Kok TM, Duckworth CA, Furlong LI, Füzi B, Gabor A, Gall L, Hengstler J, Hermjakob H, Hunter F, Jennen D, Koskinen M, Kunnen SJ, Lammens L, Lobentanzer S, Mohr M, Passini E, Pritchard DM, Malik-Sheriff RS, Rodríguez B, Rossman EI, Saez-Rodríguez J, Schmidt F, Sison-Young R, Soininen I, Turner S, van de Water B, van Hasselt JGC, Venezia F, Willy JA, Leishman DJ, Stevens JL, Laplanche L:

Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety. Nat Rev Drug Discov (2025) doi: 10.1038/s41573-025-01308-z. Epub ahead of print.

Ghallab A, Mandorfer M, Stirnimann G, Geyer J, Lindström E, Luedde T, van der Merwe S, Rashidi-Alavijeh J, Schmidt H, Karpen SJ, Fickert P, Trauner M, Hengstler JG, Dawson PA:

Enteronephrohepatic circulation of bile acids and therapeutic potential of systemic bile acid transporter inhibitors. J Hepatol 83(5): 1204-1217 (2025) doi: 10.1016/j.jhep.2025.05.009

Nell P, Thomitzek A, Feuerborn D, Scholtz-Illigens A, Seidel SM, Derksen K, Chilinski LM, Kattler-Lackes K, Blüthgen N, Morkel M, Walter J, Edlund K, Rahnenführer J, Hengstler JG:

Elimination of CDX2 restricts intestinal hybrid differentiation signatures in stem cell-derived hepatocyte-like cells. Stem Cell Res Ther 16(1): 543 (2025) doi: 10.1186/s13287-025-04696-6

Goj G, Helfferich J, El Naggar I, Noßwitz U, Bültmann E, Kumaran D, Chung J, Biebl A, Steigleder L, Holzwarth D, Wendel EM, Bevot A, Nobel HA, Hengstler JG, Cleaveland R, Panzer A, Rostasy K:

Evolution of neuroimaging features in children with acute flaccid myelitis compared to other forms of childhood myelitis. Eur J Paediatr Neurol 59: 18-22 (2025) doi: 10.1016/j.ejpn.2025.09.002

Sánchez-León CA, Reyes-Velasquez PA, van Thriel C, Nitsche MA:

An in vivo model for transcranial direct current stimulation of the motor cortex in awake mice. Brain Stimul 18(6) 1978-1989 (2025) doi: 10.1016/j.brs.2025.10.018

Wu W, Liu J, Chen X, Zhu P, Xu J, Yue J, Liu X, Fang J, Chen X, Pi J, Zheng L, Zhang Q, Zhang L, Schneider CV, Schneider KM, Trautwein C, Gao P, Reilly MP, Zhang Y, Zheng X, Liu J:

Shear stress-induced endothelial HEG1 signalling regulates vascular tone and blood pressure. Eur Heart J ehaf742 (2025) doi: 10.1093/eurheartj/ehaf742. Epub ahead of print.

Hildebrandt X, Veli Ö, Hyoubi A, Zinngrebe J, Abdallah AT, Rodefeld J, Hoffmann A, Gardeweg L, Kaya Ö, Wagner E, Lindhorst A, Poggenberg M, Wang Y, Dimmler J, Schillings J, Koci P, Bonechi F, Capuccino LV, Kiefer C, Kelepouras K, Ghosh A, Noé F, Wolfrum C, Singer M, Liccardi G, Luedde T, Yavas A, Ghallab A, Hengstler JG, Antczak P, Gericke M, Winkels H, Blüher M, Walczak H, Annibaldi A, Fischer-Posovszky P, Peltzer N:

Linear ubiquitination prevents lipodystrophy and obesity-associated metabolic syndrome. Sci Adv 11(38): eadw2539 (2025) doi: 10.1126/sciadv.adw2539

Gajewski PD, Bröde P, Claus M, Golka K, Hengstler JG, Reinders J, Watzl C, Wascher E, Getzmann S:

Changes of cognitive functions and proinflammatory cytokines across the lifespan in latent Toxoplasma gondii infection. Brain Behav Immun Health 49: 101105 (2025) doi: 10.1016/j.bbih.2025.101105.