Leitung

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Anschrift

Ardeystr. 67
44139 Dortmund

Publikationen Toxikologie

Hazari Y, Habbouche L, Garcia Lopez VA, Urra H, Diaz J, Tamburini G, Milani M, Durand S, Aprahamian F, Baxter R, Huang M, Dong XC, Gonzalez-Rojas L, Francisco SJ, Tapia-Dufey I, Vihinen H, Ratziu V, Foufelle F, Hengstler JG, Jokitalo E, Maiers JL, Plate L, Kroemer G, Bailly-Maitre B, Hetz C:

Targeting the ER stress sensor IRE1 protects the liver from fibrosis through the downregulation of the proteostasis factor P4HB/PDIA1. Hepatology 83(1): 75-93 (2026) doi: 10.1097/HEP.0000000000001335

Volkert I, Grube J, Woitok MM, Mohamed MR, Edlund K, Duda JC, Dietrich J, Schneider U, Yin G, Lin C, Erschfeld S, Berger H, Candels L, Davis RJ, Bartneck M, Kühnel MP, Guillot A, Schneider KM, Schneider CV, Jonigk D, Rahnenführer J, Tacke F, Hengstler J, Trautwein C:

Selective genetic inactivation of Caspase 8 in hepatocytes ameliorates progression of MASH following Jnk deficiency. Hepatology 83(2): 344-361 (2026) doi: 10.1097/HEP.0000000000001286

Kurze I, Jakisch E, Jakisch M, Werner F, Kowald B, Golka K, Böthig R:

Indications, feasibility safety and efficacy of dorsal rhizotomy at the level of the conus medullaris (conus deafferentation) in individuals with spinal cord injury. J Spinal Cord Med 49(1): 145-153 (2026) doi: 10.1080/10790268.2024.2442151

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Safety evaluation of jagua (genipin-glycine) blue as a food additive. EFSA J 23(12): e9738 (2025) doi: 10.2903/j.efsa.2025.9738

EFSA Panel on Contaminants in the Food Chain (CONTAM), u.a. Degen G:

Derivation of a health-based guidance value for Δ8-tetrahydrocannabinol (Δ8-THC) and its occurrence in food. EFSA J 23(11): e9735 (2025) doi: 10.2903/j.efsa.2025.9735

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Safety evaluation of d-α-tocopheryl polyethylene glycol-1000 succinate (Vitamin E TPGS) as a food additive. EFSA J 23(8): e9605 (2025) doi: 10.2903/j.efsa.2025.9605

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Safety of the proposed amendment of the specifications of the food additive E960c(i) or E960c(ii). EFSA J 23(5): e9396 (2025) doi: 10.2903/j.efsa.2025.9396

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Re-evaluation of pullulan (E 1204) as a food additive and new application for its extension of use. EFSA J 23(3): e9267 (2025) doi: 10.2903/j.efsa.2025.9267

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Safety evaluation of pea fibre concentrate (FIPEA) as food additive. EFSA J 23(3): e9255 (2025) doi: 10.2903/j.efsa.2025.9255

EFSA Panel on Food Additives and Flavourings (FAF), u.a. Degen G:

Flavouring group evaluation 418 (FGE. 418): 3-[3-(2-isopropyl-5-methyl-cyclohexyl)-ureido]-butyric acid ethyl ester. EFSA J 23(1): e9201 (2025) doi: 10.2903/j.efsa.2025.9201