Apl. Prof. Dr. rer. nat. Dr. med. Gisela Degen

Leitung der ehemaligen Forschungsgruppe

Chemikalienrisiken

Tel.: +49 / 231 1084 465
E-Mail: degen@ifado.de

Vita:

  • 1997 apl. Prof. an der Ruhr-Universität Bochum (seit 2016 im Ruhestand, weiterhin als Senior Fellow Scientist tätig)
  • 1993 Umhabilitation an die Ruhr-Universität Bochum
  • seit 1992 Leiterin der Projektgruppe "Chemikalienrisiken" am IfADo
  • 1990 Habilitation (Dr. med. habil.) für Biochemische Pharmakologie und Toxikologie; Priv.-Doz. an der Universität Würzburg
  • 1983–1992 Wiss. Mitarb./Akad. Rätin a. Z. am Institut für Toxikologie, Universität Würzburg und Teilprojektleiterin im Sonderforschungsbereich 172
  • 1979–1983 Postdoctoral Fellow am NIEHS, Research Triangle Park, N.C., USA
  • 1978 Promotion (Dr. rer. nat.; Universität Würzburg)
  • 1972 Staatsexamen in Lebensmittelchemie (Universität Würzburg)

Arbeitsgebiete:

  • Biochemische Toxikologie (Bioaktivierung und Detoxifizierung von Fremdstoffen)
  • Genotoxizität von Chemikalien (Mykotoxine, Steroide u. a.)
  • Humanbiomotoring (Biomarker of Exposure)
  • Toxikokinetik und Toxikodynamik hormonell aktiver Stoffe
  • Risikobewertung von Chemikalien
Keine weitere Betreuung von Doktor- oder Masterarbeiten mehr möglich.

Schlüsselpublikationen:

  • Sumon, A. H.; Islam, F.; Mohanto, N. C.; Kathak, R. R.; Molla, N. H.; Rana, S.; Degen, G. H.; Ali, N.: ¬The¬ presence of aflatoxin M1 in milk and milk products in Bangladesh
    Toxins (Basel) 13: (7): 440 (11 pp) (2021)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.3390/toxins13070440
  • Islam, F.; Das Trisha, A.; Hafsa, J. M.; Hasan, A.; Degen, G. H.; Ali, N.: Occurrence of aflatoxin M1 in human breast milk in Bangladesh
    Mycotoxin Res. XX: epub ahead of print (2021)
    https://doi.org/10.1007/s12550-021-00436-w
    https://static-content.springer.com/esm/art%3A10.1007%2Fs12550-021-00436-w/MediaObjects/12550_2021_436_MOESM1_ESM.docx
  • Guth, S.; Hüser, S.; Roth, A.; Degen, G.; Edlund, K.; Marchan, R.; Mühle, E.; Hengstler, J. G.: Contribution to the ongoing discussion on fluoride toxicity
    Arch. Toxicol. 95: 2571-2587 (2021)
    https://dx.doi.org/10.1007/s00204-021-03072-6
    Ich bin an dieser Arbeit interessiert
  • Ghallab, A.; Hassan, R.; Myllys, M.; Albrecht, W.; Hoehme, S.; Braeuning, A.; Degen, G. H.; Hengstler, J. G.: Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney
    Arch. Toxicol. 95: 2163-2177 (2021)
    Ich bin an dieser Arbeit interessiert
    https://dx.doi.org/10.1007/s00204-021-03073-5
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Safety of a proposed amendment of the specifications for steviol glycosides (E 960) as a food additive: to expand the list of steviol glycosides to all those identified in the leaves of Stevia Rebaudiana Bertoni.
    EFSA Journal 18: 6106 (33 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.6106
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 69, Revision 1 (FGE.69Rev1): consideration of aromatic substituted secondary alcohols, ketones and related esters evaluated by JECFA (57th meeting), structurally related to aromatic ketones from chemical group 21 evaluated by EFSA in FGE.16Rev2
    EFSA Journal 18: 6265 (35 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.6265
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 91, Revision 3 (FGE.91Rev3): consideration of aliphatic, aromatic and a,ß-unsaturated sulfides and thiols evaluated by JECFA (53rd, 61st, 68th and 76th meetings), structurally related to substances in FGE.08Rev5
    EFSA Journal 18: 6154 (49 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.6154
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 73, Revision 5 (FGE.73Rev5): consideration of alicyclic alcohols, aldehydes, acids and related esters evaluated by JECFA (59th, 63rd and 86th meeting) and structurally related to substances evaluated in FGE.12Rev5
    EFSA Journal 18: 5970 (31 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.5970
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 72, Revision 2 (FGE.72Rev2): Consideration of aliphatic, branched-chain saturated and unsaturated alcohols, aldehydes, acids and related esters evaluated by JECFA (61st, 68th and 69th meetings) and structurally related to flavouring substances in FGE.05Rev3
    EFSA Journal 18: 6029 (36 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.6029
  • Ali, N.; Degen, G. H.: Biological monitoring for ochratoxin A and citrinin and their metabolites in urine samples of infants and children in Bangladesh
    Mycotoxin Res. 36: 409-417 (2020)
    https://doi.org/10.1007/s12550-020-00407-7
    Ich bin an dieser Arbeit interessiert
  • Ali, N.; Manirujjaman, M.; Rana, S.; Degen, G. H.: Determination of aflatoxin M1 and deoxynivalenol biomarkers in infants and children urines from Bangladesh
    Arch. Toxicol. 94: 3775–3786 (2020)
    https://doi.org/10.1007/s00204-020-02857-5
    Ich bin an dieser Arbeit interessiert
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Safety of use of oat lecithin as a food additive
    EFSA Journal 18: 5969 (22 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.5969
  • Guth, S.; Hüser, S.; Roth, A.; Degen, G.; Edlund, K.; Marchan, R.; Nitsche, M. A.; van Thriel, C.: Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses
    Arch. Toxicol. 94: 1375-1415 (2020)
    https://dx.doi.org/10.1007/s00204-020-02725-2
    Ich bin an dieser Arbeit interessiert
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 61 Revision 2 (FGE.61Rev2): Consideration of aliphatic acetals evaluated by JECFA (57th, 63rd and 68th meetings) structurally related to acetals evaluated by EFSA in FGE.03Rev2
    EFSA Journal 18: 5923 (23 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.5923
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 71 Revision 1 (FGE.71Rev1): consideration of aliphatic, linear, a,b-unsaturated alcohols, aldehydes, carboxylic acids, and related esters evaluated by JECFA (63rd and 69th meeting) structurally related to flavouring substances evaluated in FGE.05Rev3
    EFSA Journal 18: 5924 (44 pp) (2020)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2020.5924
  • Ali, N.; Degen, G. H.: Citrinin biomarkers: a review of recent data and application to human exposure assessment
    Arch. Toxicol. 93: 3057-3066 (2019)
    https://doi.org/10.1007/s00204-019-02570-y
    Ich bin an dieser Arbeit interessiert
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 208 Revision 3 (FGE.208Rev3): Consideration of genotoxicity data on alicyclic aldehydes with a,ß-unsaturation in ring/side-chain and precursors from chemical subgroup 2.2 of FGE.19
    EFSA Journal 17: 5569 (50 pp) (2019)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2019.5569
  • Malir, F.; Louda, M.; Ostry, V.; Toman, J.; Ali, N.; Grosse, Y.; Pfohl-Leszkowicz, A.; Degen, G. H.: Analyses of biomarkers of exposure to nephrotoxic mycotoxins in a cohort of patients with renal tumours
    Mycotoxin Res. 35: 391-403 (2019)
    https://doi.org/10.1007/s12550-019-00365-9
    Ich bin an dieser Arbeit interessiert
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 217, Revision 2 (FGE.217Rev2): Consideration of genotoxic potential for a,ß-unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones
    EFSA Journal 17: 5568 (45 pp) (2019)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2019.5568
  • EFSA Panel on Food Additives and Flavourings; Degen, G. H.: Scientific Opinion on Flavouring Group Evaluation 210 Revision 3 (FGE.210Rev3): Consideration of genotoxic potential for a,ß-unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19
    EFSA Journal 17: 5676 (42 pp) (2019)
    Ich bin an dieser Arbeit interessiert
    https://doi.org/10.2903/j.efsa.2019.5676