Dr. Nachiket Vartak

Research Fellow

Systems Toxicology

Phone: +49 / 231 1084 464
Email: nash@ifado.de

Key publications:

  • Vartak, N.; Guenther, G.; Joly, F.; Damle-Vartak, A.; Begher-Tibbe, B.; Ghallab, A.; Drasdo, D.; Hengstler, J. G.: Intravital dynamic and correlative imaging reveals diffusion?dominated canalicular and flow?augmented ductular bile flux
    Hepatology XX: accepted ms. (2020)
    https://doi.org/10.1002/hep.31422
  • Reinders, J.; Vartak, N.; van Thriel, C.; Golka, K.; Edlund, K.: Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
    Arch. Toxicol. 93: 1609-1637 (2019)
    I am interested in this work
    http://dx.doi.org/10.1007/s00204-019-02492-9
  • Damle-Vartak, A.; Begher-Tibbe, B.; Gunther, G.; Geisler, F.; Vartak, N.; Hengstler, J. G.: Pipe-3D: a pipeline based on immunofluorescence, 3D confocal imaging, reconstructions, and morphometry for biliary network analysis in cholestasis
    In: Experimental cholestasis research (S. 25-53) / edited by Mathieu Vinken. New York: Springer Science+Business, 2019.
    (Methods in molecular biology, 1981)
    I am interested in this work
    https://doi.org/10.1007/978-1-4939-9420-5_3
  • Ghallab, A.; Vartak, N.; Hassan, R.; Zaza, A.; Godoy, P.; Drasdo, D.; Hengstler, J. G.; Reif, R.: Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood
    Hepatology 69: 666-683 (2019)
    http://dx.doi.org/10.1002/hep.30213
    I am interested in this work
  • Lorentzen, A.; Becker, P. F.; Kosla, J.; Saini, M.; Weidele, K.; Damle-Vartak, A.; Vartak, N.; Heikenwalder, M.: Single cell polarity in liquid phase facilitates tumour metastasis
    Nat. Commun. 9: 887 (20 pp.) (2018)
    I am interested in this work
    http://dx.doi.org/10.1038/s41467-018-03139-6
  • Jansen, P. L.; Ghallab, A.; Vartak, N.; Reif, R.; Schaap, F. G.; Hampe, J.; Hengstler, J. G.: ¬The¬ ascending pathophysiology of cholestatic liver disease
    Hepatology 65: 722-738 (2017)
    I am interested in this work
    http://dx.doi.org/10.1002/hep.28965
  • Vartak, N.; Damle-Vartak, A.; Richter, B.; Dirsch, O.; Dahmen, U.; Hammad, S.; Hengstler, J. G.: Cholestasis-induced adaptive remodeling of interlobular bile ducts
    Hepatology 63: 951-964 (2016)
    I am interested in this work
    http://dx.doi.org/10.1002/hep.28373
  • Reif, R.; Adawy, A.; Vartak, N.; Schröder, J.; Günther, G.; Ghallab, A.; Schmidt, M.; Hengstler, J. G.: Activated ErbB3 translocates to the nucleus via clathrin-independent endocytosis, which is associated with proliferating cells
    J. Biol. Chem. 291: 3837-3847 (2016)
    I am interested in this work
    http://dx.doi.org/10.1074/jbc.M115.686782
  • Berg, V.; Rusch, M.; Vartak, N.; Jüngst, C.; Schauss, A.; Waldmann, H.; Hedberg, C.; Pallasch, C. P.: miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL
    Blood 125: 2948-2957 (2015)
    I am interested in this work
    http://dx.doi.org/10.1182/blood-2014-07-586511
  • Reif, R.; Karlsson, J.; Günther, G.; Wrangborg, D.; Hammad, S.; Begher-Tibbe, B.; Vartak, A.; Hengstler, J. G.: Bile canalicular dynamics in hepatocyte sandwich cultures
    Arch. Toxicol. 89: 1861-1870 (2015)
    I am interested in this work
    http://dx.doi.org/10.1007/s00204-015-1575-9