PD Dr. rer. nat. Christoph van Thriel

Christoph van Thriel Head of the research group

Neurotoxicology and Chemosensation

Phone: +49 / 231 1084 407
Email: thriel@ifado.de

Curriculum Vitae:

  • since 2011 Head of the research group, “Neurotoxicology and Chemosensation”, IfADo
  • Habilitation may 2011
  • 2003-2011 Head of the research group "Neurobehavioural Toxicology", IfADo
  • 1999-2003 Post-Doc in the research group "Behavioural Toxicology", Collaboration in different research projects
  • 1999 doctoral dissertation (Dr. rer. nat.) at the Ruhr-University Bochum
  • 1996-1999 research associate in a research project on neurobehavioural effects of occupational toluene exposure at the IfADo (Prof. Dr. Seeber)
  • 1994-1996 research associate in a research project on emotional psychology at the Heinrich-Heine-University Düsseldorf (DFG supported, Prof. Dr. Ruch)
  • 1994 Diploma in psychology (Dipl.-Psych.) at the Heinrich-Heine-University Düsseldorf

Research topics:

  • physiological and psychological mechanisms of interactions between chemicals and brain structures
  • neurocognitive functioning and possible interferences with chemosensory stimulation
  • sensory neurotoxicology
  • ‘in-vitro’ neurotoxicology
  • implicit and explicit modifiers of neurobehavioural dose-response relations
  • individual differences

Publications:

  • Bahri, Marwa; Euskirchen, N. [Betreuerin]; van Thriel, C. [Erstgutachter]: ¬Der¬ AMPA Rezeptor als molekulares Target der Neurotoxizität von Tri-Ortho-Cresyl-Phosphat (ToCP): Blockiert ToCP den Einstrom von Ca2+ Ionen durch ionotrope Glutamat Rezeptoren? . ¬The¬ AMPA receptor as a molecular target of the neurotoxicity of Tri-Ortho-Cresyl Phosphate (ToCP): ToCP blocks the influx of Ca2+ ions by ionotropic glutamate receptors?Bahri, Marwa; Euskirchen, N. [Betreuerin]; van Thriel, C. [Erstgutachter]. Bochum: Univ., 2020.
    Bochum, Ruhr-Univ., Fakultät für Biologie und Biotechnologie, Masterarbeit, 2020
    I am interested in this work
  • Boyes, W. K.; van Thriel, C.: Neurotoxicology of nanomaterials
    Chem. Res. Toxicol. 33: 1121?1144 (2020)
    I am interested in this work
    https://dx.doi.org/10.1021/acs.chemrestox.0c00050
  • Guth, S.; Hüser, S.; Roth, A.; Degen, G.; Edlund, K.; Marchan, R.; Nitsche, M. A.; van Thriel, C.: Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses
    Arch. Toxicol. 94: 1375-1415 (2020)
    https://dx.doi.org/10.1007/s00204-020-02725-2
    I am interested in this work
  • Pacharra, M.; Kleinbeck, S.; Schäper, M.; Hucke, C. I.; van Thriel, C.: Sniffin’ sticks and olfactometer-based odor thresholds for n-butanol: Correspondence and validity for indoor air scenarios
    Atmosphere 11: 472 (15 pp) (2020)
    I am interested in this work
    https://dx.doi.org/10.3390/atmos11050472
  • Haanes, J. V.; Nordin, S.; Hillert, L.; Witthöft, M.; van Kamp, I.; van Thriel, C.; Van den Bergh, O.: "Symptoms associated with environmental factors“ (SAEF): Towards a paradigm shift regarding "idiopathic environmental intolerance" and related phenomena
    J. Psychosom. Res. 131: article no. 109955 (7 pp) (2020)
    I am interested in this work
    https://doi.org/10.1016/j.jpsychores.2020.109955
  • Kleinbeck, S.; Schäper, M.; Pacharra, M.; Lehmann, M. L.; Golka, K.; Blaszkewicz, M.; Brüning, T.; van Thriel, C.: ¬A¬ short-term inhalation study to assess the reversibility of sensory irritation in human volunteers
    Arch. Toxicol. 94: 1687-1701 (2020)
    https://doi.org/10.1007/s00204-020-02703-8
    I am interested in this work
  • Dreser, N.; Madjar, K.; Holzer, A. K.; van Thriel, C.; Sachinidis, A.; Rahnenführer, J.; Hengstler, J. G.; Leist, M.: Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances
    Arch. Toxicol. 94: 151-171 (2020)
    https://doi.org/10.1007/s00204-019-02612-5
    I am interested in this work
  • van Thriel, C.: Neurotoxicology: an update on epidemiology, mechanisms, and pathology
    Acta Neuropathol. 138: 339-341 (2019)
    http://dx.doi.org/10.1007/s00401-019-02051-7
    I am interested in this work
  • Wolff, Kira; van Thriel, C. [Supervisor]; Wolf, Oliver [Supervisor]: ¬A¬ nose under stress: how the SECPT affects the perception of positive and negative odorsWolff, Kira; van Thriel, C. [Supervisor]; Wolf, Oliver [Supervisor]. Bochum: Univ., 2019.
    Bochum, Univ., Faculty of Psychology, Master thesis, 2019
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  • Schmitz, C.; Welck, J.; Tavernaro, I.; Grinberg, M.; Rahnenführer, J.; van Thriel, C.; Hengstler, J. G.; Kraegeloh, A.: Mechanical strain mimicking breathing amplifies alterations in gene expression induced by SiO2 NPs in lung epithelial cells
    Nanotoxicology 13: 1227-1243 (2019)
    https://dx.doi.org/10.1080/17435390.2019.1650971
    I am interested in this work