Dr. Ahmed Ghallab

Research Fellow

Systems Toxicology

Phone: +49 / 231 1084 356
Email: ghallab@ifado.de

Key publications:

  • Schuran, F. A.; Lommetz, C.; Steudter, A.; Ghallab, A.; Wieschendorf, B.; Schwinge, D.; Reinders, J.; Carambia, A.: Aryl hydrocarbon receptor activity in hepatocytes sensitizes to hyperacute acetaminophen-induced hepatotoxicity in mice
    Cell. Mol. Gastroenterol. Hepatol. 11: 371-388 (2021)
    https://doi.org/10.1016/j.jcmgh.2020.09.002
    I am interested in this work
  • Gupta, R.; Schrooders, Y.; Hauser, D.; Albrecht, W.; Brecklinghaus, T.; Hengstler, J. G.; Ghallab, A.; Caiment, F.: Comparing in vitro human liver models to in vivo human liver using RNA-Seq
    Arch. Toxicol. 95: 573–589 (2021)
    https://doi.org/10.1007/s00204-020-02937-6
    I am interested in this work
  • Schneider, K. M.; Elfers, C.; Ghallab, A.; Schneider, C. V.; Galvez, E. J. C.; Myllys, M.; Hengstler, J. G.; Trautwein, C.: Intestinal dysbiosis amplifies acetaminophen-inducedaAcute liver injury
    Cell. Mol. Gastroenterol. Hepatol. 11: 909-933 (2021)
    https://dx.doi.org/10.1016/j.jcmgh.2020.11.002
    I am interested in this work
  • Kube, I.; Tardio, L. B.; Hofmann, U.; Ghallab, A.; Hengstler, J. G.; Fuehrer, D.; Zwanziger, D.: Hypothyroidism increases cholesterol gallstone prevalence in mice by elevated hydrophobicity of primary bile acids.
    Thyroid XX: epub ahead of print (2020)
    https://dx.doi.org/10.1089/thy.2020.0636
  • Vartak, N.; Guenther, G.; Joly, F.; Damle-Vartak, A.; Begher-Tibbe, B.; Ghallab, A.; Drasdo, D.; Hengstler, J. G.: Intravital dynamic and correlative imaging reveals diffusion?dominated canalicular and flow?augmented ductular bile flux
    Hepatology XX: accepted ms. (2020)
    https://doi.org/10.1002/hep.31422
  • Campos, G.; Ghallab, A.; Pütter, L.; Edlund, K.; Cadenas, C.; Marchan, R.; Hengstler, J. G.; Godoy, P.: Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease
    Arch. Toxicol. 94: 205-217 (2020)
    http://dx.doi.org/10.1007/s00204-019-02630-3
    I am interested in this work
  • Ghallab, A.; Myllys, M.; Holland, C. H.; Zaza, A.; Hassan, R.; Reinders, J.; Drasdo, D.; Hengstler, J. G.: Influence of liver fibrosis on lobular zonation
    Cells 8: (12): 1556 (24 pp) (2019)
    I am interested in this work
    https://doi.org/10.3390/cells8121556
  • Albrecht, W.; Kappenberg, F.; Brecklinghaus, T.; Stoeber, R.; Marchan, R.; Cadenas, C.; Ghallab, A.; Hengstler, J. G.: Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations
    Arch. Toxicol. 93: 1609-1637 (2019)
    I am interested in this work
    http://dx.doi.org/10.1007/s00204-019-02492-9
  • Ghallab, A.; Vartak, N.; Hassan, R.; Zaza, A.; Godoy, P.; Drasdo, D.; Hengstler, J. G.; Reif, R.: Bile microinfarcts in cholestasis are initiated by rupture of the apical hepatocyte membrane and cause shunting of bile to sinusoidal blood
    Hepatology 69: 666-683 (2019)
    http://dx.doi.org/10.1002/hep.30213
    I am interested in this work
  • Sezgin, S.; Hassan, R.; Zühlke, S.; Kuepfer, L.; Hengstler, J. G.; Spiteller, M.; Ghallab, A.: Spatio-temporal visualization of the distribution of acetaminophen as well as its metabolites and adducts in mouse livers by MALDI MSI
    Arch. Toxicol. 92: 2963-2977 (2018)
    I am interested in this work
    http://dx.doi.org/10.1007/s00204-018-2271-3