Dr. Doris Urlaub

Research Fellow

Immunology

Phone: +49 231 1084 248
Email: urlaub@ifado.de

Publications in Pubmed

Key publications:

  • Urlaub, D.; Wolfsdorff, N.; Hoffmann, J.-E.; Bröde, P.; Claus, M.; Wingert, S.; Renken, F.; Watzl, C.: Neutralizing antibody responses 300 days after SARS-CoV-2 infection and induction of high antibody titers after vaccination
    Eur. J. Immunol. 52: 810-815 (2022)
    https://doi.org/10.1002/eji.202149758
    I am interested in this work
  • Urlaub, D.; Wolfsdorff, N.; Durak, D.; Renken, F.; Watzl, C.: SARS-CoV-2 infection shortly after BNT162b2 vaccination results in high anti-spike antibody levels in nursing home residents and staff
    Immun. Inflamm. Dis. 9: 1702–1706 (2021)
    https://doi.org/10.1002/iid3.525
    I am interested in this work
  • Urlaub, D.; Watzl, C.: Coated latex beads as artificial cells for quantitative investigations of receptor/ligand interactions
    Curr. Protoc. Immunol. 2020: e111 (12 pp) (131)
    I am interested in this work
    https://dx.doi.org/10.1002/cpim.111
  • Anft, M.; Netter, P.; Urlaub, D.; Prager, I.; Schaffner, S.; Watzl, C.: NK cell detachment from target cells is regulated by successful cytotoxicity and influences cytokine production
    Cell. Mol. Immunol. 17: 347-355 (2020)
    https://dx.doi.org/10.1038/s41423-019-0277-2
    I am interested in this work
  • Dorsch, M.; Urlaub, D.; Bönnemann, V.; Bröde, P.; Sandusky, M.; Watzl, C.: Quantitative analysis of human NK cell reactivity using latex beads coated with defined amounts of antibodies
    Eur. J. Immunol. 50: 656-665 (2020)
    https://dx.doi.org/10.1002/eji.201948344
    I am interested in this work
  • Urlaub, D.; Zhao, S.; Blank, N.; Bergner, R.; Claus, M.; Tretter, T.; Watzl, C.; Merkt, W.: Activation of natural killer cells by rituximab in granulomatosis with polyangiitis
    Arthritis Res. Ther. 21: (1): 277 (11 pp) (2019)
    I am interested in this work
    https://dx.doi.org/10.1186/s13075-019-2054-0
  • Prager, I.; Liesche, C.; van Ooijen, H.; Urlaub, D.; Fasbender, F.; Claus, M.; Eils, R.; Watzl, C.: NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing
    J. Exp. Med. 216: 2113-2127 (2019)
    http://dx.doi.org/10.1084/jem.20181454
    http://jem.rupress.org/content/jem/suppl/2019/07/02/jem.20181454.DC1/JEM_20181454_sm.pdf
    I am interested in this work
  • Claus, M.; Urlaub, D.; Fasbender, F.: SLAM family receptors in natural killer cells – Mediators of adhesion, activation and inhibition via cis and trans interactions
    Clin. Immunol. 204: 37-42 (2019)
    https://doi.org/10.1016/j.clim.2018.10.011
    I am interested in this work
  • Liesche, C.; Sauer, P.; Prager, I.; Urlaub, D.; Claus, M.; Eils, R.; Beaudouin, J.; Watzl, C.: Single-fluorescent protein reporters allow parallel quantification of natural killer cell-mediated granzyme and caspase activities in single target cells
    Front. Immunol. 9: article 1840 (12 pp) (2018)
    http://dx.doi.org/10.3389/fimmu.2018.01840
    I am interested in this work
  • Urlaub, D.; Höfer, K.; Müller, M.-L.; Watzl, C.: LFA-1 activation in NK cells and their subsets: influence of receptors, maturation, and cytokine stimulation
    J. Immunol. 198: 1944-1951 (2017)
    I am interested in this work
    http://dx.doi.org/10.4049/jimmunol.1601004
  • Urlaub, D.; Bhat, R.; Messmer, B.; Watzl, C.: Co-activation of cultured human natural killer cells: enhanced function and decreased inhibition
    J. Toxicol. Environ. Health 79A: 1078-1084 (2016)
    I am interested in this work
    http://dx.doi.org/10.1080/15287394.2016.1219587
  • Merkt, W.; Urlaub, D.; Meinke, S.; Kammerer, R.; Watzl, C.: Inhibition of NKp30- and 2B4-mediated NK cell activation by evolutionary different human and bovine CEACAM1 receptors
    Eur. J. Immunol. 45: 2134-2142 (2015)
    I am interested in this work
    http://dx.doi.org/10.1002/eji.201445151
  • Claus, M.; Urlaub, D.; Watzl, C.: NK cell activation
    In: Encyclopedia of medical immunology (S. pp 795-805) / Ian R. Mackay ... (eds.). New York [u.a.]: Springer, 2014.
    I am interested in this work
    http://dx.doi.org/10.1007/978-0-387-84828-0_43
  • Watzl, C.; Urlaub, D.; Fasbender, F.; Claus, M.: Natural killer cell regulation - beyond the receptors
    F1000Prime Rep. 6: 87 (10 pp) (2014)
    I am interested in this work
    http://dx.doi.org/10.12703/P6-87
  • Windheim, M.; Southcombe, J. H.; Kremmer, E.; Chaplin, L.; Urlaub, D.; Falk, C. S.; Claus, M.; Watzl, C.: ¬A¬ unique secreted adenovirus E3 protein binds to the leukocyte common antigen CD45 and modulates leukocyte functions
    Proc. Natl. Acad. Sci. USA 110: E4884-E4893 (2013)
    I am interested in this work
    http://dx.doi.org/10.1073/pnas.1312420110
  • Watzl, C.; Urlaub, D.: Molecular mechanisms of natural killer cell regulation
    Front. Biosci. Landmark ed. 17: 1418-1432 (2012)
    I am interested in this work
    http://dx.doi.org/10.2741/3995
  • Hassold, N.; Seystahl, K.; Kempf, K.; Urlaub, D.; Zekl, M.; Einsele, H.; Watzl, C.; Wischhusen, J.: Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib
    Int. J. Cancer 131: E916-E927 (2012)
    I am interested in this work
  • Urlaub, D.; Watzl, C.: Töten oder leben lassen?: Mathematische Modelle ermöglichen Einblicke in die Regulationsmechanismen von Immunzellen
    Systembiologie.de 2012: (5): 8-11 (2012)
    I am interested in this work
    http://www.systembiologie.de
  • Watzl, C.; Sternberg-Simon, M.; Urlaub, D.; Mehr, R.: Understanding natural killer cell regulation by mathematical approaches
    Front. Immunol. 3: article 359 (6 pp.) (2012)
    I am interested in this work
    http://dx.doi.org/10.3389/fimmu.2012.00359
  • Mesecke, S.; Urlaub, D.; Busch, H.; Eils, R.; Watzl, C.: Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells
    Sci. Signal. 4: (175): ra36 (9 pp.) (2011)
    I am interested in this work
    http://dx.doi.org/10.1126/scisignal.2001325
  • Endt, J.; McCann, F. E.; Almeida, C. R.; Urlaub, D.; Leung, R.; Pende, D.; Davis, D. M.; Watzl, C.: Inhibitory receptor signals suppress ligation-induced recruitment of NKG2D to GM1-rich membrane domains at the human NK cell immune synapse
    J. Immunol. 178: 5606-5611 (2007)
    I am interested in this work