Current Job Offers

We are always on the lookout for employees with outstanding scientific competence, solution-oriented thinking and a high degree of commitment. Please send your application to bewerbung@ifado.de, if there are no other details in the announcement.

Here you can find the current job offers at IfADo.

‘Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. Dortmund’ (legal entity name) is a research institution institutionally funded by the German Federal Ministry of Labor and Social Affairs and the State of North Rhine-Westphalia. It is the sponsor of ’Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund’ (IfADo). IfADo explores the risks and potentials of modern work in interdisciplinary approaches. We combine the disciplines of Ergonomics, Immunology, Toxicology, Psychology and Neurosciences.


Website Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo

‘Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. Dortmund’ (legal entity name) is a research institution institutionally funded by the German Federal Ministry of Labor and Social Affairs and the State of North Rhine-Westphalia. It is the sponsor of ’Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund’ (IfADo). IfADo explores the risks and potentials of modern work in interdisciplinary approaches. We combine the disciplines of Ergonomics, Immunology, Toxicology, Psychology and Neurosciences.

The ImageTox group https://lab.vartak.org/ is looking for the following to start as soon as possible

technician (m, f, d)

for innovative projects focused on intravital imaging of mice along with conventional immunohistochemistry and molecular biology techniques.

The position is available immediately and limited to a period of 2 years. The duration may be extended subject to performance of the candidate and requirements of the project.

Description of duties

The candidate will support various projects in the group in the study of liver physiology and liver diseases.

Your Profile

  • FELASA A or B certification is required along with prior experience with animal handling mouse models, breeding etc.
  • Experience in processing of animal tissue samples and familiarity with microcopy will be an advantage
  • Prior experience or willingness to learn molecular biology – CRISPR-based techniques, gene expression knockdown, plasmid cloning for generating fluorescent fusion proteins etc. is desired
  • We do not necessarily expect pre-existing expertise in all the requirements of the project. The successful candidate will be expected to develop the necessary expertise through the guidance of experts in the group

We offer

  • A full-time position with currently 39,83 working hours per week
  • Remuneration according to the collective agreement for the public service (position EG 8 TV-L. The classification depends on the collective agreement and personal requirements)
  • All social benefits provided by working for the public service: e.g. an annual bonus, payment of benefits
  • Flexible working time models for the compatibility of family and career
  • Good accessibility by public transport
  • Attractive region with a wide range of cultural activities
  • An interesting, professional challenge in which you can contribute and expand your expertise and competence with a high degree of independence in an interdisciplinary team
  • An exciting task and many opportunities for further training

The IfADo promotes professional equality for all genders and is certified accordingly. We value diversity and therefore welcome all applications – regardless of gender, disability, nationality or ethnic and social origin.

General information about the Research Centre can be found here www.ifado.de.

Have we aroused your interest?

Then please send your meaningful application documents including the reference code “TA Vartak” until 28th of February 2022, preferably by mail to bewerbung@ifado.de.

Alternative you can send your application* by post to the following address:

Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V.
Personalabteilung
Ardeystraße 67
44139 Dortmund

Dortmund, the 07th of January 2022

*(We ask that application documents be submitted preferably by email or only in copies and not in folders, as the documents will not be returned. These will be destroyed in accordance with data protection regulations after the retention period has expired.)

 

 

 


Website Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo)

‘Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. Dortmund’ (legal entity name) is a research institution institutionally funded by the German Federal Ministry of Labor and Social Affairs and the State of North Rhine-Westphalia. It is the sponsor of ’Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund’ (IfADo). IfADo explores the risks and potentials of modern work in interdisciplinary approaches. We combine the disciplines of Ergonomics, Immunology, Toxicology, Psychology and Neurosciences.

The ImageTox group https://lab.vartak.org/ is looking for the following to start as soon as possible

a PostDoc Position (m, f, d)

for an innovative project at the interface of microscopy, computational imaging and translational medicine. The position is available immediately and initially limited to 2 years. 

Project description

The project aims to develop label-free Raman imaging coupled with machine learning based segmentation methods of hyper-spectral images.

Specific goals require the identification of Raman fingerprints as signatures of liver disease/progression in serum and tissue samples. Such a Raman fingerprint may be present at multiple scales – from spectra of sub-cellular organelles, cytoplasm, tissue structures or in global average spectra. We expect the same methodology to be applied for identification of these sub-cellular and tissue structures through Raman imaging as well. The methodology may be augmented if desired with other label-free methodologies such as 2-photon autofluorescence, fluorescence lifetime imaging, and second harmonic imaging. The machine-learning approach is required as hyperspectral imaging data is information-dense and classification of the samples into categories of interest may depend on the several features over the entire spectrum – e.g. peak shifts, changes in amplitude, changes in structure, or number of sub-cellular organelles and tissue structure. Samples used for the project will initially be derived from mouse and cellular models of disease. Eventually, validation of the findings against human patient samples is planned.

Your Profile

  • Familiarity with computational image processing in Python, ImageJ, MATLAB etc.
  • Willingness to dive deep into microscopy and imaging. Experience with Raman imaging, confocal microscopy, FLIM etc. is desirable
  • Willingness to learn or experience in processing of animal tissue samples.
  • Familiarity with basic mammalian cell culture
  • We do not necessarily expect pre-existing expertise in all the requirements of the project. The successful candidate will be expected to develop the necessary expertise through the guidance of experts in the group.
  • Ability to work independently as well as part of a team.
  • English proficiency in speaking and writing
  • master’s degree or diploma in the field of molecular biology, biochemistry, biotechnology, biology, pharmacy or a related course of studies 

We offer

  • A full-time position with currently 39,83 working hours per week
  • Remuneration according to the collective agreement for the public service (position EG 13 TV-L. The classification depends on the collective agreement and personal requirements)
  • All social benefits provided by working for the public service: e.g. an annual bonus, payment of benefits
  • Flexible working time models for the compatibility of family and career
  • Good accessibility by public transport.
  • Attractive region with a wide range of cultural activities.
  • An interesting, professional challenge in which you can contribute and expand your expertise and competence with a high degree of independence in an interdisciplinary team.
  • An exciting task and many opportunities for further training.

The IfADo promotes professional equality for all genders and is certified accordingly. We value diversity and therefore welcome all applications – regardless of gender, disability, nationality or ethnic and social origin.

General information about the Research Centre can be found here www.ifado.de.

Have we aroused your interest?

Then please send your meaningful application documents with a CV, a synopsis of previous work and publications, as well as 2 recommendation letters (optional) including the reference code “PostDoc Vartak” until 28th of February 2022, preferably by mail to bewerbung@ifado.de.

Alternative you can send your application* by post to the following address:

Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V.
Personalabteilung
Ardeystraße 67
44139 Dortmund

Dortmund, the 07th of January 2022

*(We ask that application documents be submitted preferably by email or only in copies and not in folders, as the documents will not be returned. These will be destroyed in accordance with data protection regulations after the retention period has expired.)


Website Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund

‘Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V. Dortmund’ (legal entity name) is a research institution institutionally funded by the German Federal Ministry of Labor and Social Affairs and the State of North Rhine-Westphalia. It is the sponsor of ’Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund’ (IfADo). IfADo explores the risks and potentials of modern work in interdisciplinary approaches. We combine the disciplines of Ergonomics, Immunology, Toxicology, Psychology and Neurosciences.

The Department of Toxicology is looking for the following to start as soon as possible

a PhD student (m, f, d)

The position (65%) is available immediately and is initially limited to 3 years.

Project description:

The rewiring of a cell’s metabolic capacity is now an accepted feature of cancer. However, the exact mechanism underlying these changes is still not fully understood. Lysophosphatidic acid (LPA) is a bioactive lipid that serves as an important intermediate in the synthesis and breakdown of phospholipids. It also acts as a ligand for G protein-coupled receptors at the cell membrane, leading to the activation of signaling pathways that regulate processes altered in cancer, such as survival, proliferation and migration. There are also reports that LPA levels are elevated in ovarian cancer patients. The majority of the work on LPA in cancer has focused on LPA in the extracellular environment. However, recent work by us have shown that LPA inside the cell is also associated with migration of ovarian cancer cells, as well as tumor growth of an ovarian carcinoma xenograft model, but the mechanism remains unknown. Therefore, to better understand the role of intracellular LPA in ovarian cancer, a characterization of the metabolic pathways regulating LPA levels in tumor cell lines is planned using molecular biology approaches in high grade ovarian cancer cell lines, and the effect of gene manipulation on a wide array of phenotypic endpoints, as well as intracellular lipid and metabolite levels. Finally, the potential clinical relevance of findings in vitro will be investigated using animal models of ovarian cancer.

The project, which is funded by the DFG, will be conducted at the Leibniz-Institute for Working Environment and Human Factors at TU Dortmund (IfADo), which offers excellent research conditions, including well-equipped S1 and S2 cell and molecular biology labs, an animal facility, an imaging facility with confocal, two-photon, and RAMAN microscopes, a high throughput microscopy platform, microCT, MRI and the IVIS Spectrum for whole animal imaging, a histology laboratory, analytical chemistry facility for proteomics and metabolomics analyses, FACS facility and a sequencing platform.

Your Profile:

  • Completed master’s degree or diploma in the field of molecular biology, biochemistry, biotechnology, biology, pharmacy or a related course of studies.
  • Experience with working with animals (FELASA B or C) or willing to learn.
  • Experience in cloning, cell culture, qRT-PCR, western blotting, immunohistochemistry and immunocytochemistry would additionally be beneficial.
  • Ability to work independently as well as part of a team.
  • Good multitasking, time management and data organization skills.
  • English proficiency in speaking and writing.

We offer:

  • A part-time position with currently 25,89 working hours per week
  • Remuneration according to the collective agreement for the public service (position EG 13 TV-L. The classification depends on the collective agreement and personal requirements)
  • All social benefits provided by working for the public service: e.g. an annual bonus, payment of benefits
  • Flexible working time models for the compatibility of family and career
  • An interesting, professional challenge in which you can contribute and expand your expertise and competence with a high degree of independence in an interdisciplinary team
  • An exciting task and many opportunities for further training

The IfADo promotes professional equality for all genders and is certified accordingly.

We value diversity and therefore welcome all applications – regardless of gender, disability, nationality or ethnic and social origin.

General information about the Research Centre can be found here www.ifado.de.

If you have any questions, please contact Dr. Rosemarie Marchan marchan@ifado.de.

Have we aroused your interest?

Then please send your meaningful application documents with all relevant certificates including the reference code “DFG Marchan” until 31th of January 2022, preferably by mail to bewerbung@ifado.de.

Alternative you can send your application* by post to the following address:

Forschungsgesellschaft für Arbeitsphysiologie und Arbeitsschutz e.V.
Personalabteilung
Ardeystraße 67
44139 Dortmund

Dortmund, the 15th of December 2021

*(We ask that application documents be submitted preferably by email or only in copies and not in folders, as the documents will not be returned. These will be destroyed in accordance with data protection regulations after the retention period has expired.)