New research project investigates the development of ovarian cancer

Jan 10, 2022

Ovarian cancer has a poor prognosis because it is often diagnosed at a late stage, when a cure is difficult. For this reason, researchers at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) are trying to understand the molecular mechanisms of the disease more precisely. An important feature of ovarian cancer, and cancer in general, is the reprograming of the metabolic capacity of cancer cells to facilitate their survival. In a recently funded DFG project entitled “Intracellularly derived lysophosphatidic acid (LPA) and glycerophospholipid metabolism in ovarian cancer”, key metabolic proteins and their contribution to cancer development are being analysed.

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When does liver cirrhosis develop into liver cancer? New study to identify risk factors

Aug 12, 2021

Worldwide, liver cancer is the second most common cause of cancer deaths and the incidence rate for this tumour disease is increasing. Liver cancer is usually diagnosed at an advanced stage, when only systemic therapies are possible. In a new research project, researchers from the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) therefore want to identify the risk factors for the transition from liver cirrhosis to liver cancer in order to facilitate early monitoring and intervention. The project is part of the LiSyM-Cancer project, which is funded by the German Federal Ministry of Education and Research.

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