New research project studies toluene-induced damage to the human nervous system

Sep 15, 2021

Toluene is one of the most common organic solvents used in paints, thinners, adhesives and as an additive in cosmetics. However, knowledge about the mechanisms of toluene’s effects on brain function in humans is still limited. Due to the frequent use of toluene in the workplace, researchers at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) aim to analyse the physiological, motor and cognitive effects as well as the symptoms in humans with toluene contact in more detail.

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New study shows relation between spinal cord injury and bladder cancer

Sep 14, 2021

Studies suggest that urinary bladder cancer is more likely to have a more unfavourable course in spinal cord injury patients than in non-paraplegic patients. However, many questions remain unanswered, such as the causes. A national research team with the participation of the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) has therefore analysed long-term data from patients from Germany, Austria and Switzerland with spinal cord injury who were treated without permanent catheters. The team concluded that urinary bladder cancer is a late event in the long-term course of paraplegia. Follow-up must therefore be intensified as the duration of paraplegia increases.

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Fatty liver disease promotes the formation of kidney stones

Aug 25, 2021

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in western countries, with an increasing incidence worldwide. Consequences of NAFLD can also include kidney disease and kidney stones, although the mechanisms for the development of these kidney complications as a result of NAFLD have not yet been fully explained. Researchers at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) have now published a paper on how fatty liver disease promotes the formation of kidney stones.

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Federal Research Minister Karliczek visits Mental Health Research and Treatment Centre

Aug 18, 2021

Anja Karliczek, Federal Minister of Education and Research, visited the Research and Treatment Centre for Mental Health at Ruhr-Universität Bochum on 17 August 2021. Here, researchers from different scientific disciplines work together to improve the mental health of children, young people and adults. As part of the network, the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) contributes its expertise in the field of mental health in the workplace.

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When does liver cirrhosis develop into liver cancer? New study to identify risk factors

Aug 12, 2021

Worldwide, liver cancer is the second most common cause of cancer deaths and the incidence rate for this tumour disease is increasing. Liver cancer is usually diagnosed at an advanced stage, when only systemic therapies are possible. In a new research project, researchers from the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) therefore want to identify the risk factors for the transition from liver cirrhosis to liver cancer in order to facilitate early monitoring and intervention. The project is part of the LiSyM-Cancer project, which is funded by the German Federal Ministry of Education and Research.

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Chronotype influences cognitive functions and basic parameters of human brain physiology

Aug 4, 2021

Scientists at the Leibniz Research Centre for Working Environment and Human Factors in Dortmund (IfADo) are exploring the connection between chronotype physiological processes in the human brain. The latest findings have now been published in Nature Communications. The result: Chronotypes influence human brain functions from basic physiological mechanisms to higher cognitive functions, such as perception, learning, remembering and thinking.

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Karolina Edlund receives funding for spatial resolution of tissue samples

Jul 28, 2021

The European Association for Cancer Research (EACR) regularly awards funding to researchers to be able to analyse spatial biomarkers in cancer research more precisely (European Whole Transcription Atlas Grant). This year, Karolina Edlund from the IfADo research area Toxicology is one of the winners. The scientist wants to perform spatially resolved sequencing of tissue to better understand the early forms of liver cancer (hepatocellular carcinoma).

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Occupational health protection: MAK and BAT values list 2021 published

Jul 13, 2021

The Permanent Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area of the German Research Foundation (DFG) has presented the 57th so-called MAK and BAT Values List. The list contains 95 changes and new additions this year. The Senate Commission is organized in different working groups. IfADo is part of the Neurotoxicity and Sensory Working Group, which has been significantly involved in new limits for lead.

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