Learning and Training

Principle investigators:
Patrick Gajewski, Oliver Kobald

Stefan ArnauGeorgios Athanassiou

EU Horizon 2020 “sustAge”, Leibniz Research Alliance „Healthy Ageing“

Helen Morrison and Ronny Hänold (Leibniz-Institut für Altersforschung, FLI), Julia Karbach (Goethe-Universität Frankfurt), Claudia Kardys (TÜV Rheinland), Beatrice Kuhlmann (Universität Mannheim), Claudia Voelcker-Rehage (TU Chemnitz)

Extending our research into basic sensory and cognitive functions, we investigate the consequences of age-related changes in these functions for activities of everyday life and work performance. We transfer and apply these basic research findings to work-related contexts and environments by examining life-long learning and training interventions designed to preserve and improve the cognitive abilities of older workers. In previous studies like the PFIFF 1 & 2 projects and the INNOKAT project we have successfully designed, implemented, and evaluated cognitive, physical, and stress management training interventions which can effectively improve corresponding resources in younger and older employees.

Goal of the project sustAGE is the development and evaluation of a technology-based, person-centered smart solution supporting the employment and later retirement of older adults from work. The idea is to provide older employees with a personalized recommendation system in form of a mobile device indicating the person’s current mental, physical, and motivational status. Based on this health surveillance monitoring, risk assessments, targeted prevention strategies and training interventions will be possible, intended to enhance occupational safety, productivity, and health. The EU Horizon 2020 project is conducted within an international consortium of occupational specialists, psychologists and end-users.

As a member of the Leibniz Research Alliance ‘Healthy Ageing’, we perform comparative analyses of cognitive aging and the role of training and learning in mice and humans: The Mice-to-Men project is a research initiative of the IfADo that aims at the complex interactions between external and internal factors on age-related processes across the lifespan, focusing especially on goal-directed learning and neural plasticity. The core questions are in which way living environments, nutrition, and the genetic background of the animals interact over the lifespan, and if adverse effects due to premature aging on cognitive functioning and neural plasticity can be ameliorated (or even reversed) by cognitive or physical training. Future goals are the development and refinement of translational paradigms to assess cognitive capabilities in mice and humans and the examination of inter-organ interactions, such as the relationship of liver functioning, the immune system and brain activity.


  • Gajewski, P.D. & Falkenstein, M. (2018). ERP and behavioral effects of physical and cognitive training on working memory in aging: a randomized controlled study
    Neural Plasticity, article ID 3454835.
  • Gajewski, P.D., Freude, G. & Falkenstein, M. (2017). Cognitive training sustainably improves executive functioning in middle-aged industry workers assessed by task switching: a randomized controlled ERP study. Frontiers in Human Neuroscience, 11, 81 (15 pp.).
  • Küper, K., Gajewski, P.D., Frieg, C. & Falkenstein, M. (2017). A randomized controlled ERP study on the effects of multi-domain cognitive training and task difficulty on task switching performance in older adults. Frontiers in Human Neuroscience 11, 184 (12 pp.).
  • Küper, K. & Karbach, J. (2016). Increased training complexity reduces the effectiveness of brief working memory training: evidence from short-term single and dual n-back training interventions. Journal of Cognitive Psychology, 28, 199-208.
  • Gajewski, P.D. & Falkenstein, M. (2015). Lifelong physical activity and executive functions in older age assessed by memory based task switching. Neuropsychologia, 73, 195-207.
  • Gajewski, P.D. & Falkenstein, M. (2015). Long-term habitual physical activity is associated with lower distractibility in a Stroop interference task in aging: Behavioral and ERP evidence. Brain Cognition, 98, 87-101.