Dr. Zaynab Hobloss

Scientific staff

Intravital Toxicology

+49 231 1084-275

hobloss@ifado.de

Head of department

Prof. Dr. Jan G. Hengstler

hengstler@ifado.de

+49 231 1084-348

Secretariat

Monika Turajski

turajski@ifado.de

+49 231 1084-349

Address

Ardeystr. 67
44139 Dortmund

Publications

Here you will find the Publications from 2010 onwards.

Zhou P, Hammour MM, Aspera-Werz RH, Ehnert S, Myllys M, Hobloss Z, Hassan R, González D, Hendawi R, Edlund K, Hans S, Laschke MW, Ghallab A, Hengstler JG, Nüssler AK, Maisenbacher TC:

Long-term Western diet feeding impairs hepatic vitamin D metabolism and promotes bone loss in mice. EXCLI J 25: 290-309 (2026) doi: 10.17179/excli2025-9085

Heij L, Hayat S, Reichel K, Maryam S, O'Rourke CJ, Tan X, van den Braber M, Verhoeff J, Halder M, Peisker F, Wiltberger G, Bednarsch J, Heise D, Deierl JC, Lang SA, Ulmer F, Luedde T, Dahl E, Jonigk D, Nolting J, Sivakumar S, Siveke J, Vondran F, Rocha FG, Baba HA, Hartmann S, Andersen JB, Hobloss Z, Ghallab A, Hengstler JG, Vallejo JJG, Kramann R, Neumann U:

Multimodal single-cell profiling reveals crosstalk between macrophages and stromal cells in poor prognostic cholangiocarcinoma patients. NPJ Precis Oncol (2026) doi: 10.1038/s41698-026-01292-6. Epub ahead of print.

Ghallab A, Myllys M, González D, Friebel A, Hobloss Z, Hassan R, Schmidt H, Siddiqui Q, Zhipeng D, Hendawi R, Begher-Tibbe B, Reinders J, Derksen K, Hofmann U, Duda JC, Ameis L, Möllenhoff K, Seddek A, Abdelmageed N, Strängberg E, Åkerblad P, Vucur M, Luedde T, Stirnimann G, Schwab M, Abbas T, Hild B, Schmidt H, Karpen SJ, Simbrunner B, Mandorfer M, Rahnenführer J, Edlund K, Hoehme S, Trauner M, Dawson PA, Lindström E, Hengstler JG:

Stage-dependent effects of systemic ASBT inhibition in a cholestasis-induced cholemic nephropathy mouse model. JHEP Rep 7(12): 101599 (2025) doi: 10.1016/j.jhepr.2025.101599

Ghallab A, González D, Strängberg E, Hofmann U, Myllys M, Hassan R, Hobloss Z, Brackhagen L, Begher-Tibbe B, Duda JC, Drenda C, Kappenberg F, Reinders J, Friebel A, Vucur M, Turajski M, Seddek AL, Abbas T, Abdelmageed N, Morad SAF, Morad W, Hamdy A, Albrecht W, Kittana N, Assali M, Vartak N, van Thriel C, Sous A, Nell P, Villar-Fernandez M, Cadenas C, Genc E, Marchan R, Luedde T, Åkerblad P, Mattsson J, Marschall HU, Hoehme S, Stirnimann G, Schwab M, Boor P, Amann K, Schmitz J, Bräsen JH, Rahnenführer J, Edlund K, Karpen SJ, Simbrunner B, Reiberger T, Mandorfer M, Trauner M, Dawson PA, Lindström E, Hengstler JG:

Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis. J Hepatol 80: 268-281 (2024)

Hassan R, Gerdemann A, Cramer B, Hobloss Z, Myllys M, González D, Albrecht W, Veerkamp J, Friebel A, Hoehme S, Esselen M, Degen GH, Humpf HU, Hengstler JG, Ghallab A:

Integrated data from intravital imaging and HPLC-MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats. Arch Toxicol 98: 1081-1093 (2024)

Hassan R, Hobloss Z, Myllys M, González D, Begher-Tibbe B, Reinders J, Friebel A, Hoehme S, Abdelmageed N, Abbas AA, Seddek AL, Morad SAF, Hengstler JG, Ghallab A:

Acetaminophen overdose causes a breach of the blood-bile barrier in mice but not in rats. Arch Toxicol 98: 1533-1542 (2024)

Kuhn M, Hassan R, González D, Myllys M, Hobloss Z, Degen GH, Humpf HU, Hengstler JG, Cramer B, Ghallab A:

Role of albumin in the metabolism and excretion of ochratoxin A. Mycotoxin Res 40: 433-445 (2024)

González D, Campos G, Pütter L, Friebel A, Holland CH, Holländer L, Ghallab A, Hobloss Z, Myllys M, Hoehme S, Meindl-Beinker NM, Dooley S, Marchan R, Weiss TS, Hengstler JG, Godoy P:

Role of WISP1 in stellate cell migration and liver fibrosis. Cells 13 (19): 1629 (2024) (15 pp)

Ghallab A, Kunz S, Drossel C, Billo V, Friebel A, Georg M, Göttlich R, Hobloss Z, Hassan R, Myllys M, Seddek A-l, Abdelmageed N, Dawson PA, Lindström E, Hoehme S, Hengstler JG, Geyer J:

Validation of NBD-coupled taurocholic acid for intravital analysis of bile acid transport in liver and kidney of mice. EXCLI J 23: 1330-1352 (2024)

Custodio RJP, Hobloss Z, Myllys M, Hassan R, González D, Reinders J, Bornhorst J, Weishaupt AK, Seddek AL, Abbas T, Friebel A, Hoehme S, Getzmann S, Hengstler JG, van Thriel C, Ghallab A:

Cognitive functions, neurotransmitter alterations, and hippocampal microstructural changes in mice caused by feeding on western diet. Cells 12 (18): 2331 (2023) (20 pp)