Publikationen Toxikologie

Link F, Li Y, Zhao J, Munker S, Fan W, Nwosu ZC, Yao Y, Wang S, Huang C, Liebe R, Hammad S, Liu H, Shao C, Gao C, Sun B, Török NJ, Ding H, Ebert MP, Weng H, Ten Dijke P, Drasdo D, Dooley S, Wang S:

ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation. Gut 74(3): 424-439 (2025) doi: 10.1136/gutjnl-2024-333213

Schürmeyer L, Peng C, Albrecht W, Brecklinghaus T, Baur P, Hengstler JG, Schorning K:

Design of optimal concentrations for in vitro cytotoxicity experiments. Arch Toxicol 99(1): 357-376 (2025) doi: 10.1007/s00204-024-03893-1

Fromme M, Payancé A, Mandorfer M, Thorhauge KH, Pons M, Miravitlles M, Stolk J, van Hoek B, Stirnimann G, Frankova S, Sperl J, Kremer AE, Burbaum B, Schrader C, Kadioglu A, Walkenhaus M, Schneider CV, Klebingat F, Balcar L, Kappe NN, Schaefer B, Chorostowska-Wynimko J, Aigner E, Gensluckner S, Striedl P, Roger P, Ryan J, Roche S, Vögelin M, Ala A, Bantel H, Verbeek J, Mariño Z, Praktiknjo M, Gevers TJG, Reuken PA, Berg T, George J, Demir M, Bruns T, Trautwein C, Zoller H, Trauner M, Genesca J, Griffiths WJ, Clark V, Krag A, Turner AM, McElvaney NG, Strnad P:

Longitudinal evaluation of individuals with severe alpha-1 antitrypsin deficiency (Pi∗ZZ Genotype). Gastroenterology 168(2): 367-381 (2025) doi: 10.1053/j.gastro.2024.10.010

Lin C, Kuzmanović A, Wang N, Liao L, Ernst S, Penners C, Jans A, Hammoor T, Stach PB, Peltzer M, Volkert I, Zechendorf E, Hassan R, Myllys M, Liedtke C, Herrmann A, Chakraborty G, Trautwein C, Hengstler J, Müller-Newen G, Wang J, Ghallab A, Bartneck M:

Exceptional uptake, limited protein expression: liver macrophages lost in translation of synthetic mRNA. Adv Sci (Weinh) 12(9):e2409729 (2025) doi: 10.1002/advs.202409729

Blum J, Brüll M, Hengstler JG, Dietrich DR, Gruber AJ, Dipalo M, Kraushaar U, Mangas I, Terron A, Fritsche E, Marx-Stoelting P, Hardy B, Schepky A, Escher S, Hartung T, Landsiedel R, Odermatt A, Sachana M, Koch K, Dönmez A, Masjosthusmann S, Bothe K, Schildknecht S, Beilmann M, Beltman JB, Fitzpatrick S, Mangerich A, Rehm M, Tangianu S, Zickgraf FM, Kamp H, Burger G, van de Water B, Kleinstreuer N, White A, Leist M:

The long way from raw data to NAM-based information: Overview on data layers and processing steps. ALTEX 42(1): 167-180 (2025) doi: 10.14573/altex.2412171

Gajewski PD, Bröde P, Claus M, Golka K, Hengstler JG, Watzl C, Wascher E, Getzmann S:

The association between hair cortisol and burnout is moderated by age, psychosocial, and immunological markers. Brain Behav Immun Health 43:100909 (2025) doi: 10.1016/j.bbih.2024.100909

Elurbide J, Colyn L, Latasa MU, Uriarte I, Mariani S, Lopez-Pascual A, Valbuena E, Castello-Uribe B, Arnes-Benito R, Adan-Villaescusa E, Martinez-Perez LA, Azkargorta M, Elortza F, Wu H, Krawczyk M, Schneider KM, Sangro B, Aldrighetti L, Ratti F, Casadei Gardini A, Marin JJG, Amat I, Urman JM, Arechederra M, Martinez-Chantar ML, Trautwein C, Huch M, Cubero FJ, Berasain C, G Fernandez-Barrena M, Avila MA:

Identification of PRMT5 as a therapeutic target in cholangiocarcinoma. Gut 74(1): 116-127 (2024) doi: 10.1136/gutjnl-2024-332998

Kwon Y, Gottmann P, Wang S, Tissink J, Motzler K, Sekar R, Albrecht W, Cadenas C, Hengstler JG, Schürmann A, Zeigerer A:

Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease. J Hepatol 82(1): 18-27 (2025) doi: 10.1016/j.jhep.2024.06.040

Eisenbrand G, Buettner A, Diel P, Epe B, Först P, Grune T, Haller D, Heinz V, Hellwig M, Humpf HU, Jäger H, Kulling S, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Spranger J, Steinberg P, Vieths S, Wätjen W, Hengstler JG:

Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food. Arch Toxicol. 2024 May 23. Epub ahead of print. Erratum for: Arch Toxicol. 2024 Jun;98(6):1573-1580.

Wiegand J, Franke A, Müller T, Stein K, Bantel H, Günther R, Denk G, Reuken PA, Schattenberg JM, Naumann U, Böttler T, Weber A, Zeuzem S, Hinz M, Greinert R, Berg C, Wissniowski TT, Simon KG, Trebicka J, Behrens R, Grümmer H, Hofmann WP, Dikopoulos N, Sarrazin C, Roeb E, Kremer AE, Muche M, Ringelhan M, Teufel A, Michl P, Keitel V, Marquardt JU, Kautz A, Tacke F, Piotrowski K, Köppe-Bauernfeind N, Trautwein C, Berg T:

Sub-optimal therapy of patients with primary biliary cholangitis (PBC) in the real-life stetting of the German PBC cohort. Z Gastroenterol 62(11): 1931-1942 (2024) doi: 10.1055/a-2382-7720