Publikationen Toxikologie

Castoldi M, Roy S, Angendohr C, Pellegrino R, Vucur M, Singer MT, Buettner V, Dille MA, Wolf SD, Heij LR, Ghallab A, Albrecht W, Hengstler JG, Flügen G, Knoefel WT, Bode JG, Zender L, Neumann UP, Heikenwälder M, Longerich T, Roderburg C, Luedde T:

Regulation of KIF23 by miR-107 controls replicative tumor cell fitness in mouse and human hepatocellular carcinoma. J Hepatol 82(3): 499-511 (2025) doi: 10.1016/j.jhep.2024.08.025

Arechederra M, Bik E, Rojo C, Elurbide J, Elizalde M, Kruk B, Krasnodębski M, Pertkiewicz J, Kozieł S, Grąt M, Raszeja-Wyszomirska J, Rullan M, Alkorta-Aranburu G, Oyón D, Fernández-Barrena MG, Candels LS, Białek A, Krupa Ł, Schneider KM, Urman J, Strnad P, Trautwein C, Milkiewicz P, Krawczyk M, Ávila MA, Berasain C:

Mutational Analysis of Bile Cell-Free DNA in Primary Sclerosing Cholangitis: A Pilot Study. Liver Int 45(4): e70049 (2025) doi: 10.1111/liv.70049

Kerbert AJC, Engelmann C, Habtesion A, Kumar P, Hassan M, Qi T, Volkert I, Otto T, Hall A, Khetan VU, Olde Damink S, Aguilar F, Chollet C, Brunet L, Clària J, Moreau R, Arroyo V, Coenraad MJ, Mehta G, Castelli F, Trautwein C, Fenaille F, Andreola F, Jalan R:

Hyperammonemia induces programmed liver cell death. Sci Adv 11(10): eado1648 (2025) doi: 10.1126/sciadv.ado1648

Kauth F, Bertolini A, Wendel EM, Koukou G, Naggar IE, Chung J, Baumann M, Schödl C, Lechner C, Bigi S, Blaschek A, Hengstler JG, Schimmel M, Nosadini M, Sartori S, Puthenparampil M, Van's Gravesande KS, Drenckhahn A, Nikolaus M, Kauffmann B, Thiels C, Häusler MG, Eckenweiler M, Karenfort M, Marina AD, Selek A, Öncel I, Kornek B, Reindl M, Rostásy K:

Characterization of children with early onset pediatric multiple sclerosis. Eur J Paediatr Neurol 54: 113-120 (2025) doi: 10.1016/j.ejpn.2025.01.006

Schneider AT, Koppe C, Crouchet E, Papargyriou A, Singer MT, Büttner V, Keysberg L, Szydlowska M, Jühling F, Moehlin J, Chen MC, Leone V, Mueller S, Neuß T, Castoldi M, Lesina M, Bergmann F, Hackert T, Steiger K, Knoefel WT, Zaufel A, Kather JN, Esposito I, Gaida MM, Ghallab A, Hengstler JG, Einwächter H, Unger K, Algül H, Gassler N, Schmid RM, Rad R, Baumert TF, Reichert M, Heikenwalder M, Kondylis V, Vucur M, Luedde T:

A decision point between transdifferentiation and programmed cell death priming controls KRAS-dependent pancreatic cancer development. Nat Commun 16: 1765 (2025) doi: 10.1038/s41467-025-56493-7

Engeli BE, Lachenmeier DW, Diel P, Guth S, Villar Fernandez MA, Roth A, Lampen A, Cartus AT, Wätjen W, Hengstler JG, Mally A:

Cannabidiol in Foods and Food Supplements: Evaluation of Health Risks and Health Claims. Nutrients 17(3): 489 (2025) doi: 10.3390/nu17030489

Albrecht W, Brecklinghaus T, Stolte M, Kappenberg F, Gründler L, Chen P, Cadenas C, Damm G, Edlund K, Ghallab A, Marchan R, Nell P, Reinders J, Seehofer D, Behr AC, Braeuning A, van Thriel C, Gardner I, Rahnenführer J, Hengstler JG:

Improved identification of human hepatotoxic potential by summary variables of gene expression. ALTEX 42(3): 397-412 (2025) doi: 10.14573/altex.2403272

Link F, Li Y, Zhao J, Munker S, Fan W, Nwosu ZC, Yao Y, Wang S, Huang C, Liebe R, Hammad S, Liu H, Shao C, Gao C, Sun B, Török NJ, Ding H, Ebert MP, Weng H, Ten Dijke P, Drasdo D, Dooley S, Wang S:

ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation. Gut 74(3): 424-439 (2025) doi: 10.1136/gutjnl-2024-333213

Schürmeyer L, Peng C, Albrecht W, Brecklinghaus T, Baur P, Hengstler JG, Schorning K:

Design of optimal concentrations for in vitro cytotoxicity experiments. Arch Toxicol 99(1): 357-376 (2025) doi: 10.1007/s00204-024-03893-1

Fromme M, Payancé A, Mandorfer M, Thorhauge KH, Pons M, Miravitlles M, Stolk J, van Hoek B, Stirnimann G, Frankova S, Sperl J, Kremer AE, Burbaum B, Schrader C, Kadioglu A, Walkenhaus M, Schneider CV, Klebingat F, Balcar L, Kappe NN, Schaefer B, Chorostowska-Wynimko J, Aigner E, Gensluckner S, Striedl P, Roger P, Ryan J, Roche S, Vögelin M, Ala A, Bantel H, Verbeek J, Mariño Z, Praktiknjo M, Gevers TJG, Reuken PA, Berg T, George J, Demir M, Bruns T, Trautwein C, Zoller H, Trauner M, Genesca J, Griffiths WJ, Clark V, Krag A, Turner AM, McElvaney NG, Strnad P:

Longitudinal evaluation of individuals with severe alpha-1 antitrypsin deficiency (Pi∗ZZ Genotype). Gastroenterology 168(2): 367-381 (2025) doi: 10.1053/j.gastro.2024.10.010