Dr. Rosemarie Marchan

Marchen_web Leitung der Nachwuchsgruppe

Zelluläre Toxikologie

Tel.: +49 / 231 1084 213
Fax: +49 / 231 1084 403
E-Mail:

Publikationen:

  • Leist, M.; Ghallab, A.; Marchan, R.; Godoy, P.; Reif, R.; van Thriel, C.; Cadenas, C.; Hengstler, J. G.: Adverse outcome pathways: opportunities, limitations and open questions
    Arch. Toxicol. 91: 3477-3505 (2017)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-017-2045-3
  • Marchan, R.; ...; Kaszta, D.; Anft, M.; Watzl, C.; Selinski, S.; Cadenas, C.; Hengstler, J. G.: Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma
    Cancer Res. 77: 4589-4601 (2017)
    http://dx.doi.org/10.1158/0008-5472.CAN-16-2065
    Ich bin an dieser Arbeit interessiert
  • Marchan, R.; Büttner, B.; Lambert, J.; Edlund, K.; Glaeser, I.; Blaszkewicz, M.; Leonhardt, G.; Marienhoff, L.: Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma
    Cancer Res. 77: 4589-4601 (2017)
    http://dx.doi.org/10.1158/0008-5472.CAN-16-2065
    Ich bin an dieser Arbeit interessiert
  • Gogiashvili, M.; Edlund, K.; Gianmoena, K.; Marchan, R.; Brik, A.; Andersson, J. T.; Hengstler, J. G.; Cadenas, C.: Metabolic profiling of ob/ob mouse fatty liver using HR-MAS (1)H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway:
    Anal. Bioanal. Chem. 409: 1591-1606 (2017)
    http://dx.doi.org/10.1007/s00216-016-0100-1
    Ich bin an dieser Arbeit interessiert
  • Hellwig, B.; Madjar, K.; Edlund, K.; Marchan, R.; Cadenas, C.; Heimes, A.-S.; Hengstler, J. G.; Rahnenführer, J.: Epsin family member 3 and ribosome-related genes are associated with late metastasis in estrogen receptor-positive breast cancer and long-term survival in non-small cell lung cancer using a genome-wide identification and validation strategy
    PLoS ONE 11: (12): e0167585 (18 pp.) (2016)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1371/journal.pone.0167585
  • Godoy, P.; Widera, A.; Schmidt-Heck, W.; Campos, G.; Cadenas, C.; Reif, R.; Marchan, R.; Hengstler, J. G.: Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue
    Arch. Toxicol. 90: 2513-2529 (2016)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-016-1761-4
  • Ghallab, A.; Celliere, G.; Henkel, S. G.; Godoy, P.; Blaszkewicz, M.; Reif, R.; Marchan, R.; Hengstler, J. G.: Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases
    J. Hepatol. 64: 860-871 (2016)
    http://dx.doi.org/10.1016/j.jhep.2015.11.018
    Ich bin an dieser Arbeit interessiert
  • Kim, J.-Y.; Fluri, D. A.; Marchan, R.; Boonen, K.; Mohanty, S.; Singh, P.; Hammad, S.; Hengstler, J. G.: 3D spherical microtissues and microfluidic technology for multi-tissue experiments and analysis
    J. Biotechnol. 205: 24-35 (2015)
    Ich bin an dieser Arbeit interessiert
  • Rempel, E.; Hoelting, L.; Waldmann, T.; Balmer, N. V.; Stöber, R.; Marchan, R.; van Thriel, C.; Hengstler, J. G.: A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors
    Arch. Toxicol. 89: 1599-1618 (2015)
    http://dx.doi.org/10.1007/s00204-015-1573-y
    Ich bin an dieser Arbeit interessiert
  • Stock, A.-M.; Klee, F.; Edlund, K.; Hammad, S.; Marchan, R.; Cadenas, C.; Hengstler, J. G.; Entschladen, F.: Gelsolin is associated with longer metastasis-free survival and reduced cell migration in estrogen receptor-positive breast cance
    Anticancer Res. 35: 5277-5286 (2015)
    Ich bin an dieser Arbeit interessiert
  • Lesjak, M. S.; Marchan, R.; Stewart, J. D.; Rempel, E.; Rahnenführer, J.; Hengstler, J. G.: EDI3 links choline metabolism to integrin expression, cell adhesion and spreading
    Cell Adh. Migr. 8: 499-508 (2014)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.4161/cam.29284
  • Hammad, S.; von Recklinghausen, I.; Begher-Tibbe, B.; Reif, R.; Godoy, P.; Golka, K.; Marchan, R.; Hengstler, J. G.: Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis
    Arch. Toxicol. 88: 1161-1183 (2014)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-014-1243-5
  • Cadenas, C.; van de Sandt, L.; Edlund, K.; Lohr, M.; Hellwig, B.; Marchan, R.; Schmidt, M.; Hengstler, J. G.: Loss of circadian clock gene expression is associated with tumor progression in breast cancer
    Cell Cycle 13: 3282-3291 (2014)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.4161/15384101.2014.954454
  • Godoy, P.; Cadenas, C.; Hellwig, B.; Marchan, R.; Stewart, J.; Reif, R.; Lohr, M.; Hengstler, J. G.: Interferon-inducible guanylate binding protein GBP2 is associated with better prognosis in breast cancer and indicates an efficient T cell response
    Breast Cancer 21: 491-499 (2014)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s12282-012-0404-8
  • Schug, M.; Stöber, R.; Godoy, P.; Reif, R.; Blaszkewicz, M.; Selinski, S.; Marchan, R.; Hengstler, J. G.: Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes
    Arch. Toxicol. 87: 337-345 (2013)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-012-0999-8
  • Krug, A. K.; Kolde, R.; Gaspar, J. A.; Rempel, E.; Marchan, R.; van Thriel, C.; Hengstler, J. G.; Rahnenführer, J.: Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach
    Arch. Toxicol. 87: 123-143 (2013)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-012-0967-3
  • Lohr, M.; Edlund, K.; Botling, J.; Hammad, S.; Othman, A.; Cadenas, C.; Marchan, R.; Hengstler, J. G.: The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer
    Cancer Lett. 333: 222-228 (2013)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1016/j.canlet.2013.01.036
  • Hengstler, J. G.; Marchan, R.; Leist, M.: Highlight report: towards the replacement of in vivo repated dose systemic toxicity testing. (Editorial)
    Arch. Toxicol. 86: 13-15 (2012)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1007/s00204-011-0798-7
  • Cadenas, C.; Vosbeck, S.; Hein, E. M.; Franckenstein, D.; Büttner, B.; Hammad, S.; Marchan, R.; Hengstler, J. G.: Glycerophospholipid profile in oncogene-induced senescence
    Biochim. Biophys. Acta 1821: 1256-1268 (2012)
    Ich bin an dieser Arbeit interessiert
    http://dx.doi.org/10.1016/j.bbalip.2011.11.008
  • Schmidt, M.; Hellwig, B.; Hammad, S.; Othman, A.; Cadenas, C.; Marchan, R.; Stewart, J. D.; Hengstler, J. G.: A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin kappa C as a compatible prognostic marker in human solid tumors
    Clin. Cancer Res. 18: 2695-2703 (2012)
    Ich bin an dieser Arbeit interessiert