Preliminary program
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Preliminary Program EnTox2011 (PDF)
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Preliminary Poster Program EnTox2011 (PDF)
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| Thursday, 19 May 2011 |
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| Registration |
(10:00) |
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| Welcome |
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| Chair: Prof. Dr. J. G. Hengstler |
(12:00 - 12:15) |
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Prof. Dr. Roger S. Goody, Max Planck Institute of Molecular
Physiology, Dortmund
Prof. Dr. Katja Ickstadt, Faculty of Statistics, TU Dortmund University
Prof. Dr. Jan G. Hengstler, IfADo - Leibniz Research Centre for Working
Environment and Human Factors, Dortmund |
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| Keynote Lecture |
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| Chair: Prof. Dr. J. G. Hengstler |
(12:00 - 12:15) |
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Dr. Patricio Godoy, IfADo – Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Understanding and improving in vitro hepatocyte systems: Inflammation and cholestasis gene expression signatures as novel features of primary hepatocytes in culture |
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| Coffee Break (12:45 - 13:00) |
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| Session 1: PCB case Dortmund |
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| Chair: Prof. Dr. M. Wilhelm, Prof. Dr. T. Kraus |
(13:00 - 14:30) |
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Prof. Dr. Thomas Kraus, RWTH Aachen University, Institute
of Occupational and Social Medicine, Aachen
Development of a preventive surveillance program for active and former
workers of a transformer and condenser recycling company, their family
members and employees of surrounding companies
Knut Rauchfuss, North Rhine-Westphalia State Agency for Nature, Environment
and Consumer Protection, Recklinghausen
Derivation of a health based guidance value for PCB in human blood
samples
Dr. Thomas Schettgen, RWTH Aachen University, Institute of Occupational
and Social Medicine, Aachen
Blood PCB levels of workers of a transformer recycling company, their
family members and employees of surrounding companies
Dr. Jürgen Wittsiepe, Department of Hygiene, Social and Environmental
Medicine, Ruhr-University Bochum
Levels of PCDD/F in blood samples of occupationally exposed workers
from a transformer recycling plant in Dortmund, Germany |
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Coffee Break (14:30 - 15:00) |
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| Session 2: Guided Poster Session I (In vitro, methods
and studies) |
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| Chair: Dr. W. Föllmann, Prof. Dr. G. Leng |
(15:00 - 16:15) |
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| Session 3: Neurotoxicity and toxicogenomics - Bringing
labs and rats to the chip |
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| Chair: PD Dr. C. van Thriel, Prof. Dr. E. Fritsche |
(16:15 - 18:15) |
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PD Dr. Christoph van Thriel, IfADo - Leibniz Research Centre
for Working Environment and Human Factors, Dortmund
The Network Formation Assay (NFA) - a new tool for the assessment
of neurotoxic effects of environmental chemicals
Prof. Dr. Ellen Fritsche, IUF - Leibniz Research Institute of Environmental
Medicine, Düsseldorf and RWTH Aachen University
Human Neurospheres as three dimensional cellular systems for developmental
neurotoxicity testing
Dr. Kathrin Gassmann, IUF - Leibniz Research Institute of Environmental
Medicine, Düsseldorf
Developmental neurotoxicity of PAHs: Species-specific AHR-insufficiency
protects human neural progenitor cells
Heike Hardelauf, Leibniz-Institut für Analytische Wissenschaften
- ISAS, Dortmund
Micropatterned in vitro neuronal networks for toxicity screening
Julia Sisnaiske, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Embryonic stem cell-derived neurons are a suitable tool for neurotoxicology
research
Markus Schug, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
New approaches in in vitro toxicogenomics |
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Talk at the Graduiertenkolleg 'Statistische Modellbildung'
(for statisticians) |
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| Chair: Prof Dr. K. Ickstadt |
(14:00 - 16:00) |
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Frank Geller, Statens Serum Institut, Kopenhagen, Denmark
To be announced |
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Dinner at the restaurant "Kräutergarten" (19:30) |
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| Friday, 20 May 2011 |
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| Registration |
(8:00) |
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| Keynote Lecture |
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| Chair: Prof. Dr. K. Ickstadt |
(8:15 - 8:45) |
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Dr. Silvia Selinski, IfADo - Leibniz Research Centre for Working
Environment and Human Factors, Dortmund How many SNPs do we need
to predict NAT2 phenotype? |
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| Session 4: Statistical challenges in genome-wide studies |
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| Chair: Prof. Dr. K. Ickstadt, Dr. H. Schwender |
(08:45 - 10:00) |
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Frank Geller, Statens Serum Institut, Kopenhagen, Denmark
Detoxification genes in genome-wide association studies
Prof. Dr. Jörg Rahnenführer, Faculty of Statistics, TU Dortmund
University
Prediction of progression and therapy response for cancer patients:
Are high-dimensional genomic data a blessing or a curse?
Martin Schäfer, Faculty of Statistics, TU Dortmund University
Integrative Analyses for Omics Data |
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Coffee Break (10:00 - 10:20) |
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| Session 5: Guided Poster Session II (Statistics, methods
and studies) |
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| Chair: Prof. Dr. Dr. H. M. Bolt, Dr. H.-P. Rihs |
(10:20 - 11:40) |
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| Session 6: Co-existence of newly detected and well-known environmental toxicants in NRW, biomarkers and polymorphisms I |
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| Chair: Prof. Dr. K. Golka, Dr. S. Selinski |
(11:40 - 13:15) |
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Prof. Dr. Dr. Hermann M. Bolt, IfADo - Leibniz Research
Centre for Working Environment and Human Factors, Dortmund
Environmental and occupational boron exposures in Bandirma, Turkey
Prof. Dr. Klaus Golka, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
N-acetyltransferase 2 and glutathione S-transferase M1 in colon and
rectal cancer cases from an industrialized area
Dr. Monika Kasper-Sonnenberg, Department of Hygiene, Social and Environmental
Medicine, Ruhr-University Bochum
Determination of Bisphenol A in urine from mother-child pairs. Results
from the Duisburg birth cohort
Dr. Jürgen Hölzer, Department of Hygiene, Social and Environmental
Medicine, Ruhr-University Bochum
PFOA-concentrations in blood samples of children, mothers and men
of Arnsberg - 2 years follow up |
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Lunch (13:15 - 14:15) |
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| Session 7: Co-existence of newly detected and well-known environmental toxicants in NRW, biomarkers and polymorphisms II |
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| Chair: Dr. S. Selinski, Prof. Dr. K. Golka |
(14:15 - 15:45) |
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Dr. Hans-Peter Rihs, Institute for Prevention and Occupational Medicine of
the German Social Accident Insurance (IPA), Bochum
Role of interleukin ((IL)-13 and IL-18 promoter polymorphisms in health care
workers with natural rubber latex allergy
Sabine Hertel, Institute for Medical Informatics, Biometry and Epidemiology,
University Hospital of Essen
Effects of ultra-fine air pollution on systemic inflammation in a
large German cohort
Prof. Dr. Ursula Krämer, IUF- Leibniz Research Institute of Environmental
Medicine, Düsseldorf, and PD Dr. Barbara Hoffmann, Institute for
Medical Informatics, Biometry and Epidemiology, University Hospital of
Essen
Cardiovascular and respiratory effects of fine particle exposure -
results from studies in the Ruhr Area |
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Coffee Break (15:45 - 16:15) |
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| Closing Session und Poster Award |
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| Chair: Prof. Dr. S. Kacew |
(16:15 - 17:00) |
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Prof. Dr. Dr. Hermann M. Bolt, IfADo - Leibniz Research
Centre for Working Environment and Human Factors, Dortmund
News, views and highlights of the conference
Prof. Dr. Sam Kacew
Poster Award |
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| IBS Tutorial 'Toxicology for Statisticians' |
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(17:30 - 18:15) |
| Prof. Dr. Klaus Golka, IfADo - Leibniz Research Centre for
Working Environment and Human Factors, Dortmund |
Basic principles and the role of statistics in toxicology |
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| Preliminary Poster Program |
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| Session 2: Guided Poster Session I (In vitro, methods
and studies) |
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| Chair: Dr. W. Föllmann, Prof. Dr. G. Leng |
(15:00 - 16:15) |
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In vitro & methods
Simone Scheitza, Ökotoxikologie/ Toxikologie, Trier University
Influence of long term culture of the human keratinocyte cell line
HaCaT
Dr. Wolfram Föllmann, IfADo - Leibniz Research Centre for Working
Environment and Human Factors, Dortmund
N-Acetylation of p-aminobenzoic acid and p-phenylenediamine in primary
porcine urinary bladder epithelial cells and in the human urothelial cell
line 5357
Kathrin Herbst, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Synergistic effects of benzo[a]pyrene and aromatic amines on DNA and
AhR- and NFkB- signaltransduction in urothelial cells
Dr. Sabine Plöttner, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Effects of cigarette smoke condensate on primary urothelial cells
in vitro
Ricarda Zdenka, Institut für Hygiene und Arbeitsmedizin, Essen University
Hospital
Biotransformation and genotoxic effects of monomethylarsonous acid
[MMA(III)] in methylating and non-methylating human cells
Dr. Claudia Behm, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Cytotoxic potency of mycotoxins in cultures of V79 lung fibroblast
cells
Studies
Prof Dr. Klaus Golka, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Ochratoxin A blood concentrations in healthy subjects and bladder
cancer cases from Pakistan
Katherine Muñoz, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Biological monitoring of ochratoxin A in mother-child pairs from Chile
Dr. Vera van Kampen, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Symptoms, spirometry, and serum antibody concentrations among 190
compost workers exposed to organic dust
Britta Schulze Waltrup, Faculty of Statistics, TU Dortmund University
Multivariate analysis of biological parameters from a study on boron
exposure
Benjamin Kendzia, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Cross-shift variation in occupational epidemiology - support for a
diurnal variation of biomarkers for inflammation and genotoxic effects
from a study in German male construction workers
Dr. Frank Hoffmeyer, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Biomarkers in EBC among 58 mild steel welders applying different techniques
Annette Rennert, Department of Hygiene, Social and Environmental Medicine,
Ruhr-University Bochum
DHEA-S levels in prepubertal children is positively associated with
backround exposure to PCBs and PCDD/F - Results from the Duisburg birth
cohort study |
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| Session 5: Guided Poster Session II (Statistics, methods and
studies) |
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| Chair: Prof. Dr. Dr. H. M. Bolt, Dr. H.-P. Rihs |
(10:20 - 11:40) |
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Statistics
Birte Hellwig, Faculty of Statistics, TU Dortmund University
Cancer classification from genome-wide gene expression data - how do
we find the really important genes?
Miriam Lohr, Faculty of Statistics, TU Dortmund University
Clinical prognosis based on differential gene regulatory networks
Dr. Holger Schwender, Faculty of Statistics, TU Dortmund University
Imputing Missing Genotypes with Weighted k Nearest Neighbors
Studies
Dr. Hans-Peter Rihs, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Modulation of oxidative DNA damage by repair enzymes XRCC1 and hOGG1
Torsten Klein, St. Vincenz Hospital, Menden
Indication for joint replacement and glutathione S-transferases M1
and T1 genotypes
Kristian Knoell, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Development of a strategy for biological monitoring in a chemical
plant producing 3,3'-dichlorobenzidine dihydrochloride
Emanuel Roth, Department of Urology, Paul Gerhardt Foundation, Lutherstadt
Wittenberg
Bladder cancer survival in a former industrial area in Saxony-Anhalt
Prof. Dr. Klaus Golka, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Bladder cancer in crack testers applying azo dye-based sprays to metal
bodies
PD Peter H. Roos, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Is there an association between arylamine-metabolizing CYP4B1 and
bladder cancer?
Daniel Ovsiannikov, Department of Urology, St.-Josefs-Hospital Dortmund-Hoerde
Polymorphic enzymes, urinary bladder cancer risk, and structural change
in the local industry
Dr. Anna Zimmermann, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
Miners compensated for pneumoconiosis and glutathione S-transferase
M1 genotype
Prof. Dr. Dr. Hermann M. Bolt, IfADo - Leibniz Research Centre for Working
Environment and Human Factors, Dortmund
Occupational cancers related to 1,3-propane sultone
Methods
Dr. Verena Liebers, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Assessment of airborne exposure to endotoxin and pyrogenic activity
using electrostatic dust fall collectors (EDCs)
Dr. Ingrid Sander, Institute for Prevention and Occupational Medicine
of the German Social Accident Insurance (IPA), Bochum
Development and application of mould antigen specific Enzyme-linked
Immuno Sorbent Assays (ELISA) to quantify airborne antigen exposure
Marie-Louise Lehmann, IfADo - Leibniz Research Centre for Working Environment
and Human Factors, Dortmund
A new technique to gain urothelial cells from patients via micro-brushing |
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